The Effect of Compliance With Elastic Compression Stockings On Severity Of PTS After 2 Years in Patients Who Underwent Pharmacomechanical Catheter-Directed Thrombolysis For Acute Iliofemoral Deep Vein Thrombosis.
Ali Baran Budak, Orhan Eren Günertem, Muhammet Sefa Sağla M, İhsan Alur, Tonguç Saba
{"title":"The Effect of Compliance With Elastic Compression Stockings On Severity Of PTS After 2 Years in Patients Who Underwent Pharmacomechanical Catheter-Directed Thrombolysis For Acute Iliofemoral Deep Vein Thrombosis.","authors":"Ali Baran Budak, Orhan Eren Günertem, Muhammet Sefa Sağla M, İhsan Alur, Tonguç Saba","doi":"10.1016/j.avsg.2025.09.055","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Deep Venous Thrombosis (DVT) poses significant risks, particularly Post-Thrombotic Syndrome (PTS). This study investigates the role of elastic compression stockings (ECS) in preventing PTS, focusing on patient adherence and its impact on therapeutic outcomes following pharmacomechanical catheter-directed thrombolysis (PMCDT) for acute iliofemoral DVT.</p><p><strong>Methods: </strong>This study evaluated 230 patients post-PMCDT for acute iliofemoral DVT, comparing 74 compliant and 156 non-compliant patients regarding PTS incidence and severity using Villalta and VCSS scores. Follow-ups included both clinical assessments and D-Dimer measurements, along with evaluation of adherence to elastic compression stockings.</p><p><strong>Results: </strong>The compliant group (74 patients) showed a higher proportion of females (48.7%) compared to the non-compliant group (31.0%, p=0.0435). Hospital stays were longer for compliant patients (3.91 days) than non-compliant (3.28 days, p=0.002). At the 6-month follow-up, the rate of severe PTS was 4.05% in the compliant group and 7.05% in the non-compliant group (OR=0.56; 95% CI: 0.15-2.06; p=0.05). At 24 months, severe PTS was observed in 4.05% versus 8.97% (OR=0.43; 95% CI: 0.12-1.54; p=0.05). D-Dimer levels were significantly lower in the compliant group at 6 months (1103 ng/ml vs. 1945 ng/ml, p<0.001), but not at 24 months.</p><p><strong>Conclusion: </strong>This study highlights the importance of patient adherence to ECS in reducing long-term complications following DVT treatment. Enhanced compliance strategies, including education and monitoring, are essential for improving recovery. Further research is necessary to optimize ECS use and prevent PTS.</p>","PeriodicalId":8061,"journal":{"name":"Annals of vascular surgery","volume":" ","pages":""},"PeriodicalIF":1.6000,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of vascular surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.avsg.2025.09.055","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PERIPHERAL VASCULAR DISEASE","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Deep Venous Thrombosis (DVT) poses significant risks, particularly Post-Thrombotic Syndrome (PTS). This study investigates the role of elastic compression stockings (ECS) in preventing PTS, focusing on patient adherence and its impact on therapeutic outcomes following pharmacomechanical catheter-directed thrombolysis (PMCDT) for acute iliofemoral DVT.
Methods: This study evaluated 230 patients post-PMCDT for acute iliofemoral DVT, comparing 74 compliant and 156 non-compliant patients regarding PTS incidence and severity using Villalta and VCSS scores. Follow-ups included both clinical assessments and D-Dimer measurements, along with evaluation of adherence to elastic compression stockings.
Results: The compliant group (74 patients) showed a higher proportion of females (48.7%) compared to the non-compliant group (31.0%, p=0.0435). Hospital stays were longer for compliant patients (3.91 days) than non-compliant (3.28 days, p=0.002). At the 6-month follow-up, the rate of severe PTS was 4.05% in the compliant group and 7.05% in the non-compliant group (OR=0.56; 95% CI: 0.15-2.06; p=0.05). At 24 months, severe PTS was observed in 4.05% versus 8.97% (OR=0.43; 95% CI: 0.12-1.54; p=0.05). D-Dimer levels were significantly lower in the compliant group at 6 months (1103 ng/ml vs. 1945 ng/ml, p<0.001), but not at 24 months.
Conclusion: This study highlights the importance of patient adherence to ECS in reducing long-term complications following DVT treatment. Enhanced compliance strategies, including education and monitoring, are essential for improving recovery. Further research is necessary to optimize ECS use and prevent PTS.
期刊介绍：
Annals of Vascular Surgery, published eight times a year, invites original manuscripts reporting clinical and experimental work in vascular surgery for peer review. Articles may be submitted for the following sections of the journal:
Clinical Research (reports of clinical series, new drug or medical device trials)
Basic Science Research (new investigations, experimental work)
Case Reports (reports on a limited series of patients)
General Reviews (scholarly review of the existing literature on a relevant topic)
Developments in Endovascular and Endoscopic Surgery
Selected Techniques (technical maneuvers)
Historical Notes (interesting vignettes from the early days of vascular surgery)
Editorials/Correspondence
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
