The Gut Microbiome and Cardiac Arrhythmias.

Richard A Vautier, Elaine M Sumners, Mohan K Raizada, Carl J Pepine, Ramil Goel
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Abstract

Background: The relationship between the gut microbiome and overall human health is increasingly recognized. This review discusses new research that outlines pathways and intermediaries that may mediate the interaction between the gut microbiome and cardiac arrhythmias.

Observations: Gut microbial constituents and their products have been shown to influence human physiology, including the cardiovascular system, cardiac arrhythmia, and other disease processes. The effect of the human gut microbiome on cardiovascular diseases may improve understanding of disease pathophysiologic mechanisms and presents opportunities for therapeutic modification of the gut microbiome to positively affect disease outcomes.

Conclusions: Research into the gut microbiome and its overarching impact on the human body is still in its early stages. Continued investigation of its complex relationships may lead to the development of novel therapies and strategies to enhance patient safety.

肠道微生物群与心律失常。
背景:肠道微生物群与整体人类健康之间的关系越来越被认识到。这篇综述讨论了新的研究,概述了可能介导肠道微生物群和心律失常之间相互作用的途径和中介。观察:肠道微生物成分及其产物已被证明影响人体生理,包括心血管系统、心律失常和其他疾病过程。人类肠道微生物组对心血管疾病的影响可能提高对疾病病理生理机制的理解,并为肠道微生物组的治疗性修饰提供了积极影响疾病结局的机会。结论:对肠道微生物群及其对人体的总体影响的研究仍处于早期阶段。对其复杂关系的持续研究可能会导致新的治疗方法和策略的发展,以提高患者的安全。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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