A case study of long-term disease burden in a rural community near an open burn facility.

IF 2.7 4区 医学 Q2 MEDICINE, RESEARCH & EXPERIMENTAL
Experimental Biology and Medicine Pub Date : 2025-09-18 eCollection Date: 2025-01-01 DOI:10.3389/ebm.2025.10710
Arundhati Bakshi, Liana Baconguis, Md Abdullah Al-Mamun, Qingzhao Yu, Jennifer Richmond-Bryant, Stephania A Cormier
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引用次数: 0

Abstract

Open burning and open detonation (OB/OD) of explosive and hazardous wastes creates various toxic waste products, including particulate matter, that is released into the atmosphere and capable of generating significant health impacts upon exposure. The last commercially run OB/OD thermal treatment facility in operation in the United States is located near the rural community of Colfax in central Louisiana. To evaluate the community's concerns about the potential health impacts from air pollution due to the facility's regular open burning of explosive and hazardous wastes, we examined the disease burden in Colfax compared to the surrounding parish and state. In a cross-sectional study, we analyzed hospitalizations and mortality (2000-2018) where a primary or secondary disease code was associated with cardiovascular, respiratory, thyroid and skin disease. After adjusting for age, sex and race, morbidity and mortality due to cardiovascular and respiratory diseases were significantly higher in Colfax compared to the surrounding areas. In addition, comparing age-adjusted rates across geographies, stratified by race and sex, revealed place-based differences within sub-populations. The higher estimated prevalence of disease conditions is consistent with long-term particulate matter exposure and suggests a need for comprehensive exposure studies within the community. Our data further stress the need for enhanced epidemiological studies and tailored statistical methods to address exposures and environmental health impacts in rural populations, with fewer than 2,500 individuals, like Colfax.

露天烧伤设施附近农村社区长期疾病负担个案研究
爆炸性和危险废物的露天燃烧和露天爆轰(OB/OD)产生各种有毒废物,包括释放到大气中的颗粒物质,接触后能够对健康产生重大影响。美国最后一家商业运营的OB/OD热处理设施位于路易斯安那州中部科尔法克斯的农村社区附近。为了评估社区对该设施定期露天燃烧爆炸性和危险废物造成的空气污染对健康的潜在影响的关注,我们将科尔法克斯的疾病负担与周围教区和州进行了比较。在一项横断面研究中,我们分析了与心血管、呼吸、甲状腺和皮肤疾病相关的原发性或继发性疾病代码的住院率和死亡率(2000-2018)。在对年龄、性别和种族进行调整后,科尔法克斯心血管和呼吸系统疾病的发病率和死亡率明显高于周边地区。此外,比较不同地域的年龄调整率,按种族和性别分层,揭示了亚人群中基于地点的差异。疾病状况的较高估计患病率与长期颗粒物暴露相一致,这表明有必要在社区内进行全面的暴露研究。我们的数据进一步强调,需要加强流行病学研究和量身定制的统计方法,以解决像科尔法克斯这样人口少于2,500人的农村人口的接触和环境健康影响问题。
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来源期刊
Experimental Biology and Medicine
Experimental Biology and Medicine 医学-医学:研究与实验
CiteScore
6.00
自引率
0.00%
发文量
157
审稿时长
1 months
期刊介绍: Experimental Biology and Medicine (EBM) is a global, peer-reviewed journal dedicated to the publication of multidisciplinary and interdisciplinary research in the biomedical sciences. EBM provides both research and review articles as well as meeting symposia and brief communications. Articles in EBM represent cutting edge research at the overlapping junctions of the biological, physical and engineering sciences that impact upon the health and welfare of the world''s population. Topics covered in EBM include: Anatomy/Pathology; Biochemistry and Molecular Biology; Bioimaging; Biomedical Engineering; Bionanoscience; Cell and Developmental Biology; Endocrinology and Nutrition; Environmental Health/Biomarkers/Precision Medicine; Genomics, Proteomics, and Bioinformatics; Immunology/Microbiology/Virology; Mechanisms of Aging; Neuroscience; Pharmacology and Toxicology; Physiology; Stem Cell Biology; Structural Biology; Systems Biology and Microphysiological Systems; and Translational Research.
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