Estimating the economic and societal burden of suicide and suicide attempts in India: a study protocol.

IF 2.3 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Nikhil Jain, Ben Wijnen, Isha Lohumi, Jason Madan, Silvia Evers
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Abstract

Introduction: Suicide has a substantial economic burden, yet in low- or middle-income countries, the analysis is constrained by the absence of disaggregated economic data. Existing studies primarily rely on gross costing methods, overlooking sector-specific costs such as healthcare, law enforcement and productivity losses at the family and community levels. Furthermore, the societal perspective, essential for understanding the multifaceted economic impacts of suicide, remains insufficiently explored in the Indian context.

Methods and analysis: This study will quantify the economic burden of suicide and suicide attempts in India. The initial phase will involve developing a resource-use measure instrument to capture the societal costs associated with suicide. Subsequently, a retrospective, incidence-based study will be conducted in India using the developed instrument. This will also be complemented with the Health-Related Quality of Life Assessment using EuroQOL (EQ-5D-5L). Exploratory subgroup cost comparisons (eg, suicide methods, healthcare facility type) will use non-parametric tests, including the Mann-Whitney U and Kruskal-Wallis tests. Generalised linear mixed models (gamma distribution and log link) will analyse longitudinal cost and HRQoL data, besides bootstrapping techniques and sensitivity analyses.

Ethics and dissemination: Ethics approval was obtained for the study from the institutional review board of the Indian Law Society (ILS/141/2024). All data collected during the study will adhere to ethical guidelines, taking informed consent. The findings of the study will be disseminated through peer-reviewed journals to aid data-driven decision-making.

Trial registration: Clinical Trial Registry of India (CTRI/2025/02/080380), date of registration: 12/02/2025.

估计印度自杀和自杀企图的经济和社会负担:一项研究方案。
前言:自杀具有重大的经济负担,但在低收入或中等收入国家,由于缺乏分类的经济数据,分析受到限制。现有的研究主要依赖于总成本计算方法,忽略了特定部门的成本,如家庭和社区一级的医疗保健、执法和生产力损失。此外,对于理解自杀的多方面经济影响至关重要的社会视角,在印度的背景下仍然没有得到充分的探索。方法与分析:本研究将量化印度自杀和自杀企图的经济负担。最初阶段将涉及开发一种资源使用测量工具,以捕捉与自杀有关的社会成本。随后,将利用开发的仪器在印度进行一项基于发病率的回顾性研究。这也将与使用EuroQOL (EQ-5D-5L)的健康相关生活质量评估相辅相成。探索性亚组成本比较(如自杀方法、医疗机构类型)将使用非参数检验,包括Mann-Whitney U和Kruskal-Wallis检验。广义线性混合模型(伽马分布和日志链接)将分析纵向成本和HRQoL数据,以及自启动技术和敏感性分析。伦理和传播:该研究获得了印度法律协会机构审查委员会(ILS/141/2024)的伦理批准。在研究过程中收集的所有数据都将遵守伦理准则,并获得知情同意。这项研究的结果将通过同行评议的期刊传播,以帮助数据驱动的决策。试验注册:印度临床试验注册中心(CTRI/2025/02/080380),注册日期:12/02/2025。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
BMJ Open
BMJ Open MEDICINE, GENERAL & INTERNAL-
CiteScore
4.40
自引率
3.40%
发文量
4510
审稿时长
2-3 weeks
期刊介绍: BMJ Open is an online, open access journal, dedicated to publishing medical research from all disciplines and therapeutic areas. The journal publishes all research study types, from study protocols to phase I trials to meta-analyses, including small or specialist studies. Publishing procedures are built around fully open peer review and continuous publication, publishing research online as soon as the article is ready.
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