The decision-making process in general practice of when to use antibiotics to treat acute rhinosinusitis.

Abstract

Background: The Danish primary care sector is responsible for the majority of antibiotic prescriptions, with upper respiratory tract infections, particularly acute rhinosinusitis (ARS), being a key contributor. This study explored the decision-making process regarding antibiotic use for ARS among general practitioners (GPs) and doctors in training working in general practice.

Methods: Nine semi-structured interviews were conducted with 10 doctors. Interviews were audio-recorded, transcribed verbatim and analyzed using systematic text condensation.

Results: Four key themes were developed: (1) 'It all starts before the consultation': staff-led triage shaping ARS care, (2) two diagnostic worlds: experienced intuition vs. rule-bound caution, (3) C-reactive protein (CRP) in the crossfire: guide, reassurance or irrelevant in antibiotic decision-making and (4) 'Sometimes it's a negotiation': managing patient expectations without losing stewardship. Although diagnosing ARS was often straightforward, distinguishing bacterial from viral infections proved difficult. C-reactive protein testing was common, but its reliability was questioned. Antibiotic prescribing decisions were influenced by patient history, comorbidities and risk factors. While antibiotics were rarely considered necessary initially, patient expectations and doctor-patient relationships sometimes influenced prescribing.

Conclusions: This study illustrates the complexity of diagnosing and managing ARS, shaped by clinical uncertainty, competing priorities and non-clinical pressures. Variation in doctor involvement, diagnostic practices and CRP thresholds reveals the challenges of standardization. Training, guidelines and patient education are valued but may not ensure optimal antibiotic use. Diagnostic decisions are relational, negotiated and context-specific, influenced by public health concerns, patient needs and workflow demands. Without acknowledging this complexity, antibiotic stewardship efforts could potentially fall short.