Racial Variation in Cerebral Near Infrared Spectroscopy Accuracy Among Infants in a Cardiac Intensive Care Unit.

IF 1.2 4区医学 Q3 OBSTETRICS & GYNECOLOGY

American journal of perinatology Pub Date : 2025-10-03 DOI:10.1055/a-2714-3293

Callie Marshall, Stephanie Diggs, Morgan Pfeiffer, Anna Gerst, Alexa Brumfiel, Zachary A Vesoulis

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引用次数: 0

Abstract

Objective: Pulse oximeters overestimate arterial oxygen saturations in black versus white adults, children, and infants. While race's impact on near-infrared spectroscopy (NIRS) accuracy is less studied, some adult research suggests decreased accuracy in black patients. This study investigates the effect of race on NIRS accuracy in infants in a cardiac intensive care unit (CICU).

Study design: A retrospective chart review was conducted for infants admitted to St. Louis Children's Hospital CICU from 2017-2023. Bland-Altman plots, Pearson correlations, and mean biases were analyzed.

Result: 254 infants (13% Black, 87% White) provided 3,687 central venous oxygen saturation (ScvO₂)-cerebral regional oxygen saturation (rScO₂) pairs. Measurement bias was -3.2% in Black infants and +0.1% in White infants (p<0.01).

Conclusion: Cerebral NIRS underestimates ScvO₂ in Black infants but maintains negligible measurement bias in White infants. This is the first study to assess race and NIRS accuracy in infants; the difference is statistically significant but not clinically relevant in most contexts.

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心脏重症监护病房婴儿大脑近红外光谱准确度的种族差异。

目的：脉搏血氧仪高估黑人与白人成人、儿童和婴儿的动脉血氧饱和度。虽然种族对近红外光谱（NIRS）准确性的影响研究较少，但一些成人研究表明，黑人患者的准确性有所下降。本研究探讨了种族对心脏重症监护病房（CICU）婴儿近红外光谱准确性的影响。研究设计：对2017-2023年圣路易斯儿童医院CICU收治的婴儿进行回顾性图表回顾。分析Bland-Altman图、Pearson相关性和均值偏差。结果：254名婴儿（13%黑人，87%白人）提供了3,687对中心静脉血氧饱和度(ScvO2)-脑区域血氧饱和度（rScO2）。黑人婴儿的测量偏倚为-3.2%，白人婴儿的测量偏倚为+0.1%(结论：黑人婴儿的脑NIRS低估了ScvO2，但白人婴儿的测量偏倚保持可忽略不计。这是第一个评估婴儿种族和近红外光谱准确性的研究；这种差异在统计学上是显著的，但在大多数情况下没有临床相关性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

American journal of perinatology 医学-妇产科学

CiteScore

5.90

自引率

0.00%

发文量

302

审稿时长

4-8 weeks

期刊介绍： The American Journal of Perinatology is an international, peer-reviewed, and indexed journal publishing 14 issues a year dealing with original research and topical reviews. It is the definitive forum for specialists in obstetrics, neonatology, perinatology, and maternal/fetal medicine, with emphasis on bridging the different fields. The focus is primarily on clinical and translational research, clinical and technical advances in diagnosis, monitoring, and treatment as well as evidence-based reviews. Topics of interest include epidemiology, diagnosis, prevention, and management of maternal, fetal, and neonatal diseases. Manuscripts on new technology, NICU set-ups, and nursing topics are published to provide a broad survey of important issues in this field. All articles undergo rigorous peer review, with web-based submission, expedited turn-around, and availability of electronic publication. The American Journal of Perinatology is accompanied by AJP Reports - an Open Access journal for case reports in neonatology and maternal/fetal medicine.