{"title":"Uniting Advanced Practice Nurses for Better Cancer Care: A Primer on Chimeric Antigen Receptor T-cell Therapy for Community-Based APNs","authors":"May San-Rozano","doi":"10.1016/j.nurpra.2025.105541","DOIUrl":null,"url":null,"abstract":"<div><div>Chimeric antigen receptor (CAR) T-cell therapy represents a transformative approach in oncology and is increasingly being administered in outpatient settings. Community-based advanced practice nurses (APNs) play a vital role in ensuring safe and coordinated care during and after treatment. This article offers a practical primer for nononcology APNs that focuses on CAR T-cell therapy’s mechanisms, logistics, toxicities, and long-term considerations. Emphasizing early recognition, collaborative care, and patient education, the article aims to strengthen APNs’ confidence and competence in co-managing this high-risk population. As the landscape of cellular therapy evolves, equipping APNs with foundational knowledge is critical for enhancing survivorship and reducing preventable complications.</div></div>","PeriodicalId":101233,"journal":{"name":"The Journal for Nurse Practitioners","volume":"21 10","pages":"Article 105541"},"PeriodicalIF":0.0000,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Journal for Nurse Practitioners","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1555415525002247","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Chimeric antigen receptor (CAR) T-cell therapy represents a transformative approach in oncology and is increasingly being administered in outpatient settings. Community-based advanced practice nurses (APNs) play a vital role in ensuring safe and coordinated care during and after treatment. This article offers a practical primer for nononcology APNs that focuses on CAR T-cell therapy’s mechanisms, logistics, toxicities, and long-term considerations. Emphasizing early recognition, collaborative care, and patient education, the article aims to strengthen APNs’ confidence and competence in co-managing this high-risk population. As the landscape of cellular therapy evolves, equipping APNs with foundational knowledge is critical for enhancing survivorship and reducing preventable complications.
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