A structured education program for improving cardiovascular risk and glycaemic control in type 2 diabetes mellitus (the SUGAR study).

IF 2.3
Mark P Ranasinghe, Marly Ranasinghe, Mayurathan Balachandran, Vinay Goel, Sulochi Subasinghe, Shane Nanayakkara
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Abstract

Aims: Structured community-based diabetes education programs may improve cardiometabolic outcomes, yet objective evidence remains limited. We evaluated the efficacy of a multidisciplinary education program in improving glycaemic control and cardiovascular risk factors in adults with type 2 diabetes mellitus (T2DM).

Methods: Adults with T2DM participated in a four-week program comprising weekly two-hour sessions on diabetes and cardiovascular disease, nutrition, exercise, and mental health. HbA1c, body mass index (BMI), weight, blood pressure, and lipid profile were assessed at baseline and at 3, 6, and 12 months. Outcomes were analysed using pooled linear mixed-effects models with multiple imputation, with sensitivity analyses excluding participants requiring pharmacotherapy escalation.

Results: Fifty participants (median age 49 years; 38 % female) completed the program. HbA1c improved significantly and was sustained at 12 months (-1.57 % (95 %CI(-1.96, -1.17), p < 0.001). LDL cholesterol (-0.51 mmol/L (95 %CI(-0.71,-0.30), p < 0.001), triglycerides (-0.86 mmol/L (95 %CI(-1.34,-0.39), p = 0.001), and BMI (-1.45 kg/m², 95 %CI(-1.99,-0.91), p < 0.001) also improved at 12 months. These findings were supported by sensitivity analysis for HbA1c, but attenuated for other cardiometabolic parameters at 12 months.

Conclusions: A structured, multidisciplinary community-based education program was associated with significant improvements in glycaemic control and key parameters of cardiometabolic risk. As a cost-efficient model, it offers a scalable strategy for T2DM management in primary care, warranting further evaluation of interactions with pharmacotherapy.

一项改善2型糖尿病心血管风险和血糖控制的结构化教育计划(SUGAR研究)。
目的:有组织的社区糖尿病教育项目可能改善心脏代谢结果,但客观证据仍然有限。我们评估了多学科教育项目在改善成人2型糖尿病(T2DM)患者血糖控制和心血管危险因素方面的效果。方法:成年T2DM患者参加了一个为期四周的项目,包括每周两小时的糖尿病和心血管疾病、营养、运动和心理健康会议。在基线、3个月、6个月和12个月时评估HbA1c、体重指数(BMI)、体重、血压和血脂。结果分析使用多重归因的合并线性混合效应模型,并进行敏感性分析,排除需要增加药物治疗的参与者。结果:50名参与者(中位年龄49岁;38% %女性)完成了该计划。HbA1c显著改善并持续12个月(-1.57 %(95 %CI(-1.96, -1.17), p )结论:一个结构化的、多学科的社区教育项目与血糖控制和心脏代谢风险关键参数的显著改善有关。作为一种具有成本效益的模式,它为初级保健中的T2DM管理提供了一种可扩展的策略,值得进一步评估与药物治疗的相互作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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