Coronary physiology in the catheterization laboratory: current practices, historical insights, and future directions.

Q4 Medicine
Cardiology Plus Pub Date : 2025-07-01 Epub Date: 2025-09-29 DOI:10.1097/CP9.0000000000000131
Simone Fezzi, Carlotta Rossignoli, Ludovica Guerrieri, Daixin Ding, Jiayue Huang, Gabriele Pesarini, Domenico Tavella, Roberto Scarsini, Flavio Ribichini, William Wijns, Shengxian Tu
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引用次数: 0

Abstract

Coronary flow improvement and myocardial ischemia relief are the primary goals of coronary revascularization. The pioneering work of Andreas Gruntzig, who demonstrated the reduction of trans-stenotic pressure gradients following percutaneous coronary intervention (PCI), marked a major milestone in the field. Since then, a variety of invasive and non-invasive techniques for assessing coronary physiology have been developed. These methods play a pivotal role in evaluating the hemodynamic significance of coronary lesions, guiding PCI planning, optimizing post-PCI outcomes, and assessing coronary microcirculation and disease patterns. This review explores the available tools for coronary physiology assessment in the catheterization laboratory and their applications in the decision-making process for coronary revascularization. In addition, it highlights recent technological advances, such as invasive and coronary image-based computational methods. These innovations enable individualized PCI treatment, aiming for complete ischemia relief through optimized morpho-functional procedural outcomes.

导管实验室的冠状动脉生理学:当前实践,历史见解和未来方向。
冠状动脉血流改善和心肌缺血缓解是冠状动脉血运重建术的主要目的。Andreas Gruntzig的开创性工作,证明了经皮冠状动脉介入治疗(PCI)后跨狭窄压力梯度的降低,标志着该领域的一个重要里程碑。从那时起,各种评估冠状动脉生理的侵入性和非侵入性技术被开发出来。这些方法在评估冠状动脉病变血流动力学意义、指导PCI计划、优化PCI后预后、评估冠状动脉微循环和疾病模式等方面发挥着关键作用。本文综述了导管实验室中可用的冠状动脉生理评估工具及其在冠状动脉重建术决策过程中的应用。此外,它还强调了最近的技术进步,例如侵入性和基于冠状动脉图像的计算方法。这些创新实现了个体化PCI治疗,旨在通过优化形态功能的手术结果完全缓解缺血。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
0.50
自引率
0.00%
发文量
24
审稿时长
32 weeks
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