Characterization of the Medscint HYPERSCINT scintillation dosimetry research platform with orthovoltage photon beams and a novel quasi monoenergetic beam.

IF 3.4 3区 医学 Q2 ENGINEERING, BIOMEDICAL
Leonard Che Fru, Benjamin Abraham Insley, Dongyoen Lee, Dirk Alan Bartkoski, Reza Reiazi, Aviad Schori, Ramesh Tailor, Mohammad R Salehpour
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Abstract

Objective: This work aimed to evaluate the dosimetric characteristics of the new HyperScintTM Research Platform 200 system (HS-RP200), with orthovoltage beams and a novel kilovoltage converging beam, Converging Radiotherapy and Radiosurgery (CRnR) beam.

Approach: Several dosimetric properties of the HS-RP200 detector with several orthovoltage beams were studied in air. Relative dosimetry of the HS-RP200 detector was also studied for use on the converging x-ray beam. Energy correction factors were compared between measurement, Monte Carlo, and analytical methods.

Main results: The signal-to-noise ratio (SNR) for the detector increased as the frame exposure time increased, and repeated measurements had less uncertainty when measurements were performed without stem-effect removal (WOSER). The short-term stability study of the detector's signal showed an acceptable variance of its readings to within 1% during one-hour measurements. The detector exhibited angular independence within the measurement uncertainty of 1%. The detector exhibited excellent dose linearity response with the orthovoltage beams. During an 80-day period, repeated measurements determined that the detector possesses long-term stability within a root mean square (rms) of 2.3% and 0.6% when measurements were performed with stem effect removal (WSER) and WOSER, respectively. Calculated energy correction factors implied significant fluctuations of the HS-RP200 detector with the beam quality of orthovoltage beams, ranging from 3% to 66%, depending on the divergence of the effective energy of the beam from reference quality. Monte Carlo-simulated energy correction factors agreed with measurements with a maximum difference of 5.4% when measurements were performed WOSER. Lastly, the HS-RP200 detector system exhibited good relative dosimetric characteristics with the CRnR beam. A maximum rms value of 0.019 was calculated for the normalized profiles when measurements from the HS-RP200 detector were compared to measurements from film.

Significance: The HS-RP200 detector could be used as an alternative to other detectors with orthovoltage beams, including the CRnR beam.

Medscint HYPERSCINT闪烁剂量学研究平台的正交电压光子束和新型准单能光束的表征。
目的:本工作旨在评估新型HyperScintTM研究平台200系统(HS-RP200)的剂量学特性,该系统具有正电压束和新型千伏会聚束,会聚放疗和放射外科(CRnR)束。方法:研究了HS-RP200探测器在空气中几种正压光束的剂量学特性。本文还研究了HS-RP200探测器在会聚x射线光束上的相对剂量学。比较了测量法、蒙特卡罗法和分析法的能量校正因子。主要结果:检测器的信噪比(SNR)随着帧曝光时间的增加而增加,并且在不进行干效应去除(WOSER)的情况下,重复测量的不确定度较小。探测器信号的短期稳定性研究表明,在一小时测量期间,其读数的可接受方差在1%以内。在1%的测量不确定度范围内,探测器具有角无关性。探测器对正电压光束具有良好的剂量线性响应。在80天的时间内,重复测量确定,当分别使用干效应去除(WSER)和WSER进行测量时,检测器具有在2.3%和0.6%的均方根(rms)内的长期稳定性。计算得到的能量修正系数表明,HS-RP200探测器随正压光束光束质量的显著波动,波动范围在3%到66%之间,这取决于光束有效能量与参考质量的差异。蒙特卡罗模拟的能量校正因子与WOSER测量结果一致,最大差异为5.4%。最后,HS-RP200探测器系统在CRnR光束下表现出良好的相对剂量学特性。当HS-RP200探测器测量值与胶片测量值进行比较时,计算出归一化轮廓的最大均方根值为0.019。意义:HS-RP200探测器可作为其他正压波束探测器的替代品,包括CRnR波束。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Physics in medicine and biology
Physics in medicine and biology 医学-工程:生物医学
CiteScore
6.50
自引率
14.30%
发文量
409
审稿时长
2 months
期刊介绍: The development and application of theoretical, computational and experimental physics to medicine, physiology and biology. Topics covered are: therapy physics (including ionizing and non-ionizing radiation); biomedical imaging (e.g. x-ray, magnetic resonance, ultrasound, optical and nuclear imaging); image-guided interventions; image reconstruction and analysis (including kinetic modelling); artificial intelligence in biomedical physics and analysis; nanoparticles in imaging and therapy; radiobiology; radiation protection and patient dose monitoring; radiation dosimetry
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