Multi-factor vaccination game and optimal control of a SVIS epidemic model.

IF 1.9 4区 生物学 Q2 BIOLOGY
Na Liu, Jia Wang, Jie Fang, Junwei Sun, Qixun Lan, Wei Deng
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引用次数: 0

Abstract

Infectious diseases represent a major global health challenge, characterized by their abrupt onset and rapid transmission, leading to millions of deaths annually. Vaccination can not only protect individuals, but also establish a group immune barrier to effectively prevent the spread of diseases, which is crucial in the prevention and control of infectious diseases. However, individual vaccination decisions are affected by many factors, typically to maximize personal benefits. Therefore, a SVIS epidemic network model based on complete information is proposed, and the stability of the equilibrium points is analyzed by using Jacobian matrix and Lyapunov stability theory. This study explores vaccination behavior within the framework of game theory, in which individuals seek to maximize their own benefits through strategic decision-making. However, such self-interested behavior often results in high social costs. Subsequently, to address the gap between individual income and social cost, we propose an optimal control strategy that minimizes societal costs while ensuring sufficient coverage to suppress transmission. Finally, The simulation results not only validate the efficacy of game-theoretic approaches, but also demonstrate their capability to achieve optimal control with minimized social costs. In addition, the simulation results also show that network structure has a significant impact on the speed and scope of disease transmission, and the social benefits are different in different network environments.

SVIS流行病模型的多因素疫苗接种对策与最优控制。
传染病是一项重大的全球卫生挑战,其特点是发病突然、传播迅速,每年导致数百万人死亡。接种疫苗不仅可以保护个体,还可以建立群体免疫屏障,有效防止疾病的传播,这在传染病的预防和控制中至关重要。然而,个人接种疫苗的决定受到许多因素的影响,通常是为了最大化个人利益。为此,提出了一种基于完全信息的SVIS流行病网络模型,并利用雅可比矩阵和Lyapunov稳定性理论分析了平衡点的稳定性。本研究探讨了博弈论框架下的疫苗接种行为,在博弈论框架下,个体通过战略决策寻求自身利益最大化。然而,这种自私自利的行为往往会导致高昂的社会成本。随后,为了解决个人收入与社会成本之间的差距,我们提出了一种最优控制策略,在确保足够的覆盖范围以抑制传播的同时,使社会成本最小化。最后,仿真结果不仅验证了博弈论方法的有效性,而且证明了它们能够以最小的社会成本实现最优控制。此外,仿真结果还表明,网络结构对疾病传播的速度和范围有显著影响,不同网络环境下的社会效益也不同。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Biosystems
Biosystems 生物-生物学
CiteScore
3.70
自引率
18.80%
发文量
129
审稿时长
34 days
期刊介绍: BioSystems encourages experimental, computational, and theoretical articles that link biology, evolutionary thinking, and the information processing sciences. The link areas form a circle that encompasses the fundamental nature of biological information processing, computational modeling of complex biological systems, evolutionary models of computation, the application of biological principles to the design of novel computing systems, and the use of biomolecular materials to synthesize artificial systems that capture essential principles of natural biological information processing.
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