A comparative evaluation of surface dose values: radiochromic film measurements versus computational predictions from different radiotherapy planning algorithms.

IF 2 4区 医学 Q3 ENGINEERING, BIOMEDICAL
Ibrahim Kaptan, Yucel Akdeniz, Emine Burcin Ispir
{"title":"A comparative evaluation of surface dose values: radiochromic film measurements versus computational predictions from different radiotherapy planning algorithms.","authors":"Ibrahim Kaptan, Yucel Akdeniz, Emine Burcin Ispir","doi":"10.1007/s13246-025-01648-5","DOIUrl":null,"url":null,"abstract":"<p><p>Accurate prediction of surface doses is crucial for clinical outcomes in radiotherapy. Surface dose distribution must be predicted accurately by calculation algorithms in the treatment planning system (TPS). This study aims to compare surface dose calculations from the Eclipse TPS with radiochromic film measurements to evaluate the reliability of these calculation algorithms. Measurements with radiochromic films were performed using 6 MV photon beams. Treatment plans for 3D conformal radiotherapy (3DCRT), intensity-modulated radiotherapy (IMRT), and volumetric arc therapy (VMAT) were generated on the TPS and calculated using various algorithms. Treatment plans were irradiated on Gafchromic EBT3 films with a PTW head and neck phantom. EBT3 films were compared to calculation algorithms via FilmQA™ Pro (version 7.0) software with multi-channel analysis. Dosimetric evaluations were statistically analyzed. Commercial calculation algorithms underestimated the surface dose in 3DCRT, IMRT, and VMAT treatment plans. For 3DCRT, the underestimations were 8.0% with the AAA algorithm and 8.7% with AXB. In VMAT, the underestimations were 10.2% with AAA and 12.9% with AXB. For IMRT, the underestimations were 6.6% with AAA and 7.3% with AXB. The AAA algorithm closely matched surface dose measurements among calculation methods. The dosimetric results indicate that both AAA and AXB algorithms, as implemented in the Eclipse™ TPS, tend to underestimate surface dose compared to EBT3 film measurements. Accurate knowledge of the dose in the superficial region is crucial to prevent acute skin reactions or to deliver an effective dose to superficial tumors in clinically significant cases. Therefore, our surface dose measurements offer more accurate evaluations, making Gafchromic EBT3 films suitable for such cases.</p>","PeriodicalId":48490,"journal":{"name":"Physical and Engineering Sciences in Medicine","volume":" ","pages":""},"PeriodicalIF":2.0000,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Physical and Engineering Sciences in Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s13246-025-01648-5","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
引用次数: 0

Abstract

Accurate prediction of surface doses is crucial for clinical outcomes in radiotherapy. Surface dose distribution must be predicted accurately by calculation algorithms in the treatment planning system (TPS). This study aims to compare surface dose calculations from the Eclipse TPS with radiochromic film measurements to evaluate the reliability of these calculation algorithms. Measurements with radiochromic films were performed using 6 MV photon beams. Treatment plans for 3D conformal radiotherapy (3DCRT), intensity-modulated radiotherapy (IMRT), and volumetric arc therapy (VMAT) were generated on the TPS and calculated using various algorithms. Treatment plans were irradiated on Gafchromic EBT3 films with a PTW head and neck phantom. EBT3 films were compared to calculation algorithms via FilmQA™ Pro (version 7.0) software with multi-channel analysis. Dosimetric evaluations were statistically analyzed. Commercial calculation algorithms underestimated the surface dose in 3DCRT, IMRT, and VMAT treatment plans. For 3DCRT, the underestimations were 8.0% with the AAA algorithm and 8.7% with AXB. In VMAT, the underestimations were 10.2% with AAA and 12.9% with AXB. For IMRT, the underestimations were 6.6% with AAA and 7.3% with AXB. The AAA algorithm closely matched surface dose measurements among calculation methods. The dosimetric results indicate that both AAA and AXB algorithms, as implemented in the Eclipse™ TPS, tend to underestimate surface dose compared to EBT3 film measurements. Accurate knowledge of the dose in the superficial region is crucial to prevent acute skin reactions or to deliver an effective dose to superficial tumors in clinically significant cases. Therefore, our surface dose measurements offer more accurate evaluations, making Gafchromic EBT3 films suitable for such cases.

表面剂量值的比较评估:放射性致色膜测量与不同放射治疗计划算法的计算预测。
表面剂量的准确预测对放射治疗的临床结果至关重要。在治疗计划系统(TPS)中,必须通过计算算法准确地预测表面剂量分布。本研究旨在比较Eclipse TPS计算的表面剂量与放射致色膜测量的结果,以评估这些计算算法的可靠性。用6毫伏的光子束对放射性变色薄膜进行了测量。在TPS上生成三维适形放疗(3DCRT)、调强放疗(IMRT)和体积弧治疗(VMAT)的治疗方案,并使用各种算法计算。治疗方案在带有PTW头颈假体的Gafchromic EBT3薄膜上照射。通过FilmQA™Pro (version 7.0)软件进行多通道分析,将EBT3胶片与计算算法进行比较。对剂量学评价进行统计学分析。商业计算算法低估了3DCRT、IMRT和VMAT治疗方案的表面剂量。对于3DCRT, AAA算法和AXB算法分别低估了8.0%和8.7%。在VMAT中,AAA组低估10.2%,AXB组低估12.9%。对于IMRT, AAA组和AXB组的低估率分别为6.6%和7.3%。在各种计算方法中,AAA算法与表面剂量测量结果吻合较好。剂量学结果表明,与EBT3膜测量相比,Eclipse™TPS中实现的AAA和AXB算法都倾向于低估表面剂量。准确了解浅表区域的剂量对于预防急性皮肤反应或在临床重要病例中向浅表肿瘤提供有效剂量至关重要。因此,我们的表面剂量测量提供了更准确的评估,使Gafchromic EBT3薄膜适用于此类情况。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
8.40
自引率
4.50%
发文量
110
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信