Association between heated tobacco product use and worsening asthma symptoms: findings from a nationwide internet survey in Japan, 2023.

IF 2.5 3区医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Environmental Health and Preventive Medicine Pub Date : 2025-01-01 DOI:10.1265/ehpm.25-00197

Shingo Noguchi, Tomohiro Ishimaru, Kazuhiro Yatera, Yoshihisa Fujino, Takahiro Tabuchi

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引用次数: 0

Abstract

Background: Heated tobacco products (HTPs) are widely used in Japan, following cigarettes, but their health effects remain unclear. HTPs are often considered a less harmful alternative to cigarettes and are commonly used by adults with asthma, even though smoking is one of the most obvious and treatable factors in asthma. We aimed to elucidate the association between HTP use and asthma symptoms in adults with asthma.

Methods: A total of 3,787 individuals with asthma were extracted from the data in the Japan COVID-19 and Society Internet Survey 2023, an ongoing longitudinal internet-based cohort study conducted by a nationwide internet research company in Japan. They were categorized into three groups (never, past, and current smokers) based on cigarette use. The association between HTP use and worsening of asthma symptoms within the previous 2 months in each group was analyzed using univariate and multivariate logistic regression analyses. Both exposure and outcomes were assessed by self-reporting.

Results: Among the participants, 2,470 (65.2%) were never smokers, 845 (22.3%) were past smokers, and 472 (12.5%) were current smokers. Overall, the proportion of HTP users was 429 (11.3%), and worsened asthma symptoms were observed in 400 (10.6%) individuals. The total proportion of HTP users and worsened asthma symptoms was 70 (2.8%) and 259 (10.5%) among never smokers, 180 (21.3%) and 72 (8.5%) among past smokers, and 179 (37.9%) and 69 (14.6%) among current smokers. After adjusting for confounders, the odds ratio (OR) was 3.25 (95% confidence interval [CI] 1.86-5.68, p < 0.001), 1.47 (95% CI 0.93-2.34, p = 0.1), and 2.23 (95% CI 1.46-3.43, p < 0.001) for never, past, and current cigarette smokers with HTP use, respectively, where never smokers without HTP use were set as the standard.

Conclusion: The use of HTPs, not only cigarette smoking, was associated with worsening of asthma symptoms in adults with asthma. Therefore, people need to understand the harmful effects of HTPs on asthma symptoms.

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加热烟草产品使用与哮喘症状恶化之间的关系：2023年日本全国互联网调查的结果。

背景：加热烟草制品（HTPs）在日本广泛使用，仅次于香烟，但其对健康的影响尚不清楚。htp通常被认为是一种危害较小的香烟替代品，并且通常被患有哮喘的成年人使用，尽管吸烟是哮喘最明显和可治疗的因素之一。我们的目的是阐明成人哮喘患者使用HTP与哮喘症状之间的关系。方法：从日本一家全国性互联网研究公司正在进行的基于互联网的纵向队列研究《日本COVID-19和社会互联网调查2023》的数据中提取3787名哮喘患者。他们根据吸烟情况被分为三组（从不吸烟、过去吸烟和现在吸烟）。采用单因素和多因素logistic回归分析分析各组前2个月内HTP使用与哮喘症状恶化之间的关系。暴露和结果均通过自我报告进行评估。结果：在参与者中，2470人（65.2%）为从不吸烟者，845人（22.3%）为过去吸烟者，472人（12.5%）为当前吸烟者。总体而言，HTP使用者的比例为429人（11.3%），400人（10.6%）出现哮喘症状恶化。从不吸烟者中HTP使用者和哮喘症状加重的总比例分别为70（2.8%）和259(10.5%)，过去吸烟者中180（21.3%）和72(8.5%)，目前吸烟者中179（37.9%）和69（14.6%）。调整混杂因素后，从不吸烟、过去吸烟和现在吸烟且使用HTP的比值比（OR）分别为3.25（95%可信区间[CI] 1.86-5.68, p < 0.001）、1.47 （95% CI 0.93-2.34, p = 0.1）和2.23 (95% CI 1.46-3.43, p < 0.001)，其中从不吸烟且不使用HTP作为标准。结论：成人哮喘患者哮喘症状的恶化与使用htp有关，而不仅仅是吸烟。因此，人们需要了解htp对哮喘症状的有害影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Environmental Health and Preventive Medicine PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH -

CiteScore

7.90

自引率

2.10%

发文量

审稿时长

10 weeks

期刊介绍： The official journal of the Japanese Society for Hygiene, Environmental Health and Preventive Medicine (EHPM) brings a comprehensive approach to prevention and environmental health related to medical, biological, molecular biological, genetic, physical, psychosocial, chemical, and other environmental factors. Environmental Health and Preventive Medicine features definitive studies on human health sciences and provides comprehensive and unique information to a worldwide readership.