Hypoxia Following Mitral Transcatheter Edge-to-Edge Repair

Q4 Medicine

JACC. Case reports Pub Date : 2025-10-01 DOI:10.1016/j.jaccas.2025.105305

Fajer J. Almoosa MD , Mamdouh A. Elsmaan MD, MSc , Michael L. Rigby MD , Saeed Mirsadraee MD, PhD , Ali H. Vazir MB, BS, PhD

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Abstract

Background

Mitral regurgitation (MR) is a common disorder associated with increased risk of morbidity and mortality. Transcatheter edge-to-edge repair (TEER) is a minimally invasive option that is increasingly used in the management of this condition. Randomized controlled trials have concluded that TEER is safe and effective in reducing secondary MR.

Case Summary

An 81-year-old woman underwent mitral TEER for severe secondary MR. She suffered from ongoing hypoxia postprocedure because of an iatrogenic fistula between the right main pulmonary artery and left atrium with right to left shunt.

Discussion

This case represents a unique and rare complication of mitral TEER.

Take-Home Messages

Rare but life-threatening complications of mitral TEER should be recognized in a timely manner. Finally, clinicians should consider filter-based cerebral protection system during TEER; however, further studies on its utility are warranted.

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二尖瓣经导管边缘对边缘修复术后缺氧

背景：二尖瓣反流（MR）是一种常见的疾病，与发病率和死亡率增加有关。经导管边缘到边缘修复（TEER）是一种微创选择，越来越多地用于治疗这种疾病。随机对照试验得出结论，TEER在降低继发性mr方面是安全有效的。病例总结：一名81岁女性因严重继发性mr接受二尖瓣TEER治疗，由于右肺动脉主动脉和左心房之间的医源性瘘伴右至左分流，术后持续缺氧。本病例是一种独特而罕见的二尖瓣TEER并发症。应及时认识到二尖瓣TEER罕见但危及生命的并发症。最后，临床医生应考虑在TEER中建立基于过滤器的脑保护系统；然而，对其效用的进一步研究是必要的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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