DB-1305/BNT325, a novel trophoblast cell-surface antigen 2 antibody-drug conjugate, in patients with ovarian cancer: Efficacy and safety data from a phase I/II study

IF 4.1 2区医学 Q1 OBSTETRICS & GYNECOLOGY

Gynecologic oncology Pub Date : 2025-09-01 DOI:10.1016/j.ygyno.2025.03.061

Maria Rubinstein , Bhavana Pothuri , Hua Yang , Omkar Marathe , Alexander Spira , Harshad Amin , Nashat Gabrail , Lihong Lin , Aaron Lisberg , Zhu Qiao , Qingming Zhang , An Lin , Wu Zhuang , Sascha Tillmanns , Darlington Akahara , Peizhen Miao , Wei Gu , Bin Zhang , Xiaodong Sun , Yang Qiu , Jianqing Zhu

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一种新型滋养细胞表面抗原- 2抗体-药物偶联物DB-1305/BNT325用于卵巢癌患者：来自I/II期研究的疗效和安全性数据

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Gynecologic oncology 医学-妇产科学

CiteScore

8.60

自引率

6.40%

发文量

1062

审稿时长

37 days

期刊介绍： Gynecologic Oncology, an international journal, is devoted to the publication of clinical and investigative articles that concern tumors of the female reproductive tract. Investigations relating to the etiology, diagnosis, and treatment of female cancers, as well as research from any of the disciplines related to this field of interest, are published. Research Areas Include: • Cell and molecular biology • Chemotherapy • Cytology • Endocrinology • Epidemiology • Genetics • Gynecologic surgery • Immunology • Pathology • Radiotherapy