Phuong H Bao, David R Friedland, Jazzmyne A Adams, Julie K Freed, Masoud Khani, Jake Luo
{"title":"Assessment of Anesthetic Modalities in Otologic Surgery.","authors":"Phuong H Bao, David R Friedland, Jazzmyne A Adams, Julie K Freed, Masoud Khani, Jake Luo","doi":"10.1097/ONO.0000000000000075","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>Otologic surgery has specific anesthetic requirements such as avoiding nitrous oxide and allowing facial nerve monitoring, but lacks clear criteria for an optimal anesthetic regimen, often relying on anesthesiologist preference.</p><p><strong>Study design: </strong>This study is a retrospective review of 600 primary cochlear implant surgeries and anesthetic variables.</p><p><strong>Setting: </strong>This study was conducted in a tertiary academic medical center.</p><p><strong>Methods: </strong>Univariate, multivariate, and cluster analyses of anesthetic regimen association with clinical metrics of postoperative recovery.</p><p><strong>Results: </strong>Among 600 cochlear implant surgeries, anesthesia regimens included balanced (combination of gas and intravenous agents) (84.3%), gas alone (13.5%), and total intravenous anesthesia (TIVA) (2.2%). By univariate analysis, emergence from anesthesia was shortest with TIVA (11.9 ± 4.6 minutes) and longest with gas (14.2 ± 5.3 minutes), although not reaching statistical significance. Univariate analyses also failed to show a significant correlation between anesthesia regimen and phase I recovery or phase II duration. Multivariate regression indicated significantly shorter emergence times with TIVA compared with gas alone (coeff: -5.29, <i>P</i> = 0.0027). Cluster analysis identified 3 groups based on relative remifentanil and gas usage. Patients in cluster 1 (low gas and high remifentanil) had significantly longer emergence times than those in clusters 2 (low gas, low remifentanil: 16.26 ± 5.96 vs 13.39 ± 5.30 minutes; <i>P</i> = 0.001) and 3 (high gas, low remifentanil: 16.26 ± 5.96 vs 13.47 ± 5.48 minutes; <i>P</i> = 0.0069). Cluster 1 also had longer phase 1 recovery times compared with clusters 2 (65.33 ± 28.87 vs 54.33 ± 25.36 minutes; <i>P</i> = 0.0085) and 3 (65.33 ± 28.87 vs 56.38 ± 20.81 minutes; <i>P</i> = 0.0365).</p><p><strong>Conclusion: </strong>TIVA anesthetic regimen is associated with shorter emergence time than gas alone, although the difference in time is small. Balanced regimens are most used among anesthesiologists, and limiting remifentanil dosage may shorten emergence and recovery times.</p>","PeriodicalId":74382,"journal":{"name":"Otology & neurotology open","volume":"5 3","pages":"e075"},"PeriodicalIF":1.3000,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12466899/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Otology & neurotology open","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1097/ONO.0000000000000075","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/9/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: Otologic surgery has specific anesthetic requirements such as avoiding nitrous oxide and allowing facial nerve monitoring, but lacks clear criteria for an optimal anesthetic regimen, often relying on anesthesiologist preference.
Study design: This study is a retrospective review of 600 primary cochlear implant surgeries and anesthetic variables.
Setting: This study was conducted in a tertiary academic medical center.
Methods: Univariate, multivariate, and cluster analyses of anesthetic regimen association with clinical metrics of postoperative recovery.
Results: Among 600 cochlear implant surgeries, anesthesia regimens included balanced (combination of gas and intravenous agents) (84.3%), gas alone (13.5%), and total intravenous anesthesia (TIVA) (2.2%). By univariate analysis, emergence from anesthesia was shortest with TIVA (11.9 ± 4.6 minutes) and longest with gas (14.2 ± 5.3 minutes), although not reaching statistical significance. Univariate analyses also failed to show a significant correlation between anesthesia regimen and phase I recovery or phase II duration. Multivariate regression indicated significantly shorter emergence times with TIVA compared with gas alone (coeff: -5.29, P = 0.0027). Cluster analysis identified 3 groups based on relative remifentanil and gas usage. Patients in cluster 1 (low gas and high remifentanil) had significantly longer emergence times than those in clusters 2 (low gas, low remifentanil: 16.26 ± 5.96 vs 13.39 ± 5.30 minutes; P = 0.001) and 3 (high gas, low remifentanil: 16.26 ± 5.96 vs 13.47 ± 5.48 minutes; P = 0.0069). Cluster 1 also had longer phase 1 recovery times compared with clusters 2 (65.33 ± 28.87 vs 54.33 ± 25.36 minutes; P = 0.0085) and 3 (65.33 ± 28.87 vs 56.38 ± 20.81 minutes; P = 0.0365).
Conclusion: TIVA anesthetic regimen is associated with shorter emergence time than gas alone, although the difference in time is small. Balanced regimens are most used among anesthesiologists, and limiting remifentanil dosage may shorten emergence and recovery times.
目的:耳科手术有特定的麻醉要求,如避免使用氧化亚氮和允许面神经监测,但缺乏明确的最佳麻醉方案标准,通常依赖于麻醉医师的偏好。研究设计:本研究是对600例初次人工耳蜗手术和麻醉变量的回顾性分析。背景:本研究在三级学术医疗中心进行。方法:对麻醉方案与术后恢复临床指标的关系进行单因素、多因素和聚类分析。结果:600例人工耳蜗手术中,麻醉方案包括平衡麻醉(气体与静脉联合麻醉)(84.3%)、单独麻醉(13.5%)和静脉全麻醉(TIVA)(2.2%)。单因素分析显示,TIVA麻醉苏醒时间最短(11.9±4.6分钟),气体麻醉苏醒时间最长(14.2±5.3分钟),两者差异无统计学意义。单变量分析也未能显示麻醉方案与I期恢复或II期持续时间之间的显著相关性。多因素回归分析显示,与单纯气体治疗相比,TIVA治疗的急诊时间显著缩短(coff: -5.29, P = 0.0027)。聚类分析根据相对瑞芬太尼和气体使用量确定了3组。第1组(低气、高瑞芬太尼)患者的急诊时间明显长于第2组(低气、低瑞芬太尼:16.26±5.96 vs 13.39±5.30 min, P = 0.001)和第3组(高气、低瑞芬太尼:16.26±5.96 vs 13.47±5.48 min, P = 0.0069)。与第2组(65.33±28.87 vs 54.33±25.36分钟,P = 0.0085)和第3组(65.33±28.87 vs 56.38±20.81分钟,P = 0.0365)相比,第1组的第1期恢复时间也更长。结论:与单纯气体麻醉相比,TIVA麻醉方案的急救时间较短,但差异不大。麻醉师大多使用平衡方案,限制瑞芬太尼的剂量可以缩短急救和恢复时间。