Bridging academia and industry: advancing systems biology and QSP education through AstraZeneca's collaborative partnerships.

IF 2.3
Frontiers in systems biology Pub Date : 2025-09-12 eCollection Date: 2025-01-01 DOI:10.3389/fsysb.2025.1627214
Cesar Pichardo-Almarza, Holly Kimko
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Abstract

Collaborations between industry leaders and academia are crucial for advancing systems biology education and training. This article explores opportunities for partnerships to enhance the educational landscape and develop a workforce skilled in systems modelling, particularly for quantitative systems pharmacology (QSP) in drug development. Companies with a strong focus on innovation frequently explore collaborative ventures involving joint research, co-designed curricula, and specialized training programs. These partnerships provide students and researchers with insights into real-world applications of systems biology and QSP. We explicitly review success criteria for collaboration at MSc and PhD levels, discuss earlier pipeline considerations, and carefully balance the roles, incentives, and challenges for both academia and industry in collaborative ventures. Challenges in aligning academic and industry objectives exist, including resource allocation and intellectual property concerns. However, the importance of training skilled systems biologists for advancing drug discovery and development outweighs these challenges. The article concludes by highlighting successful industry-academia partnerships and offering recommendations for optimizing collaborations to meet the evolving needs of systems biology education and drive innovation in pharmaceutical research.

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连接学术界和工业界:通过阿斯利康的合作伙伴关系推进系统生物学和QSP教育。
业界领袖和学术界之间的合作对于推进系统生物学教育和培训至关重要。本文探讨了合作伙伴关系的机会,以加强教育景观和发展系统建模方面的技能,特别是药物开发中的定量系统药理学(QSP)。注重创新的公司经常探索包括联合研究、共同设计课程和专门培训项目在内的合作企业。这些合作伙伴关系为学生和研究人员提供了对系统生物学和QSP的实际应用的见解。我们明确地回顾了硕士和博士阶段合作的成功标准,讨论了早期的考虑因素,并仔细平衡了学术界和工业界在合作企业中的角色、激励和挑战。在协调学术和行业目标方面存在挑战,包括资源分配和知识产权问题。然而,培训熟练的系统生物学家对于推进药物发现和开发的重要性超过了这些挑战。文章最后强调了成功的产学研伙伴关系,并为优化合作提供了建议,以满足系统生物学教育不断发展的需求,并推动制药研究的创新。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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