Right ventricular injury during VV-ECMO for severe ARDS: Does time matter?

IF 1.4 Q3 CRITICAL CARE MEDICINE
Robert McDonald, Jo-Anne Fowles, Robert Gatherer, Francisca Caetano
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引用次数: 0

Abstract

Right ventricular injury (RVI) is a frequent complication during veno-venous extracorporeal membrane oxygenation (VV-ECMO) for severe respiratory failure. In this single-centre retrospective cohort of 40 patients, RVI was observed in 63%, being associated with increased ICU mortality. RVI at admission was more common in younger patients and those with shorter intubation periods pre-cannulation. RVI developing during VV-ECMO was associated with longer ECMO support, ICU stay, and a trend towards higher mortality. The timing of RVI likely reflects different pathophysiology, having different clinical implications. Improved monitoring of right ventricular function during VV-ECMO may enable earlier detection and intervention, potentially improving outcomes.

VV-ECMO治疗严重ARDS时右室损伤:时间重要吗?
右心室损伤(RVI)是静脉-静脉体外膜氧合(VV-ECMO)治疗严重呼吸衰竭的常见并发症。在这个40例患者的单中心回顾性队列中,63%的患者观察到RVI,与ICU死亡率增加有关。入院时RVI在年轻患者和插管前插管时间较短的患者中更为常见。VV-ECMO期间发生的RVI与更长的ECMO支持、ICU住院时间和更高的死亡率趋势相关。RVI的时间可能反映了不同的病理生理,具有不同的临床意义。在VV-ECMO期间改善对右心室功能的监测可能有助于早期发现和干预,潜在地改善预后。
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来源期刊
Journal of the Intensive Care Society
Journal of the Intensive Care Society Nursing-Critical Care Nursing
CiteScore
4.40
自引率
0.00%
发文量
45
期刊介绍: The Journal of the Intensive Care Society (JICS) is an international, peer-reviewed journal that strives to disseminate clinically and scientifically relevant peer-reviewed research, evaluation, experience and opinion to all staff working in the field of intensive care medicine. Our aim is to inform clinicians on the provision of best practice and provide direction for innovative scientific research in what is one of the broadest and most multi-disciplinary healthcare specialties. While original articles and systematic reviews lie at the heart of the Journal, we also value and recognise the need for opinion articles, case reports and correspondence to guide clinically and scientifically important areas in which conclusive evidence is lacking. The style of the Journal is based on its founding mission statement to ‘instruct, inform and entertain by encompassing the best aspects of both tabloid and broadsheet''.
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