A foundational architecture for AI agents in healthcare.

IF 10.6 1区医学 Q1 CELL BIOLOGY

Cell Reports Medicine Pub Date : 2025-09-26 DOI:10.1016/j.xcrm.2025.102374

Fei Liu, Yue Niu, Qihua Zhang, Kai Wang, Zheyi Dong, Io Nam Wong, Linling Cheng, Ting Li, Lian Duan, Kun Li, Gen Li, Tai Wa Hou, Manson Fok, Huiyan Luo, Xiangmei Chen, Kang Zhang, Yun Yin

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引用次数: 0

Abstract

Medical AI agents represent a transformative paradigm in healthcare, distinguished from traditional AI by their autonomy, adaptability, and ability to manage complex tasks. This review introduces a conceptual framework for these agents built on four core components: planning, action, reflection, and memory. We examine the framework's application across key clinical domains, from enhancing diagnostic accuracy and personalizing treatment to guiding robotic surgery and enabling real-time patient monitoring. The review critically analyzes implementation challenges, including technical integration, clinician adoption, regulatory adaptation, and ethical considerations like data privacy and algorithmic bias. Future directions are explored, including the shift toward proactive, multi-agent collaborative systems and the visionary AI Agent Hospital concept. While these agents hold immense potential to revolutionize healthcare delivery by improving efficiency and patient outcomes, their successful and equitable integration hinges on navigating these profound technical, ethical, and regulatory hurdles.

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医疗保健领域人工智能代理的基础架构。

医疗人工智能代理代表了医疗保健领域的变革范式，与传统人工智能的区别在于它们的自主性、适应性和管理复杂任务的能力。这篇综述介绍了一个基于四个核心组件的智能体概念框架：计划、行动、反思和记忆。我们研究了该框架在关键临床领域的应用，从提高诊断准确性和个性化治疗到指导机器人手术和实现患者实时监测。该综述批判性地分析了实施挑战，包括技术整合、临床医生采用、监管适应以及数据隐私和算法偏见等伦理考虑。探讨了未来的发展方向，包括向主动、多智能体协作系统的转变，以及有远见的人工智能代理医院概念。虽然这些代理具有巨大的潜力，可以通过提高效率和患者治疗效果来彻底改变医疗保健服务，但它们的成功和公平整合取决于克服这些深刻的技术、道德和监管障碍。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cell Reports Medicine Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (all)

CiteScore

15.00

自引率

1.40%

发文量

231

审稿时长

40 days

期刊介绍： Cell Reports Medicine is an esteemed open-access journal by Cell Press that publishes groundbreaking research in translational and clinical biomedical sciences, influencing human health and medicine. Our journal ensures wide visibility and accessibility, reaching scientists and clinicians across various medical disciplines. We publish original research that spans from intriguing human biology concepts to all aspects of clinical work. We encourage submissions that introduce innovative ideas, forging new paths in clinical research and practice. We also welcome studies that provide vital information, enhancing our understanding of current standards of care in diagnosis, treatment, and prognosis. This encompasses translational studies, clinical trials (including long-term follow-ups), genomics, biomarker discovery, and technological advancements that contribute to diagnostics, treatment, and healthcare. Additionally, studies based on vertebrate model organisms are within the scope of the journal, as long as they directly relate to human health and disease.