Electrocardiographic Predictors for Early Risk Stratification: 30-Day Mortality in Older Adult Trauma Patients.

IF 2.9 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Sedat Ozdemir, Mehmet Murat Oktay, Iffet Tiftikci, Kazim Ersin Altinsoy
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引用次数: 0

Abstract

Objectives: This prospective observational study aimed to assess the prognostic value of electrocardiographic (ECG) findings obtained at emergency department (ED) admission in adult patients presenting with trauma-related fractures, with a focus on their association with 30-day all-cause mortality. Materials and Methods: A total of 391 patients aged ≥18 years with trauma-induced fractures were enrolled at a tertiary emergency center between February and May 2025. Baseline demographic and clinical data, including comorbidities, trauma mechanisms, and 12-lead ECG findings at admission, were recorded. Patients were monitored for 30-day mortality. Logistic regression analysis was used to identify independent predictors of mortality. Results: The mean age of the patients was 73.9 ± 6.7 years, and 50.1% were female. Normal sinus rhythm was the most common ECG finding (31.5%), followed by sinus tachycardia (20.5%) and bundle branch block (15.3%), while atrial fibrillation (AF) was present in 9.5% of cases. Thirty-day mortality occurred in 5.1% of the cohort (n = 20). Non-survivors had significantly higher frequencies of AF (35.0% vs. 8.1%, p = 0.001), head trauma (70.0% vs. 18.1%, p < 0.001), cerebrovascular disease (55.0% vs. 16.4%, p < 0.001), and polypharmacy (100% vs. 62.8%, p = 0.001) compared with survivors. Conversely, low-energy falls were more common among survivors (74.7% vs. 20.0%, p < 0.001), whereas falls from stairs or a bed and high-energy trauma were significantly more frequent among non-survivors (all p < 0.05). In multivariate logistic regression, AF (OR: 6.112; 95% CI: 1.612-23.176; p = 0.008), head trauma (OR: 16.514; 95% CI: 4.925-55.367; p < 0.001), and cerebrovascular disease (OR: 6.725; 95% CI: 2.219-20.385; p = 0.001) emerged as independent predictors of 30-day mortality. Although normal sinus rhythm was associated with survival in univariate analysis (p = 0.034), it did not retain independent significance in multivariate modeling. Patients with AF had significantly lower 30-day survival compared with those without AF (65.0% vs. 96.3%, p = 0.001). Conclusions: This prospective study demonstrates that electrocardiographic abnormalities-especially atrial fibrillation-are strong predictors of 30-day mortality in older adult trauma patients. Their prognostic value was further reinforced when assessed alongside head trauma and cerebrovascular disease. These findings emphasize ECG as a rapid, practical, and noninvasive tool for early risk stratification and clinical decision-making in the emergency care of geriatric fracture patients.

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早期危险分层的心电图预测指标:老年创伤患者30天死亡率。
目的:本前瞻性观察性研究旨在评估急诊(ED)收治的创伤性骨折成年患者的心电图(ECG)结果的预后价值,重点关注其与30天全因死亡率的关系。材料和方法:2025年2月至5月在三级急救中心登记了391例年龄≥18岁的创伤性骨折患者。记录基线人口统计学和临床数据,包括合并症、创伤机制和入院时12导联心电图结果。监测患者30天死亡率。采用Logistic回归分析确定死亡率的独立预测因子。结果:患者平均年龄73.9±6.7岁,女性占50.1%。正常的窦性心律是最常见的心电图表现(31.5%),其次是窦性心动过速(20.5%)和束支传导阻滞(15.3%),而房颤(AF)出现在9.5%的病例中。30天死亡率为5.1% (n = 20)。与幸存者相比,非幸存者的AF(35.0%比8.1%,p = 0.001)、头部创伤(70.0%比18.1%,p < 0.001)、脑血管疾病(55.0%比16.4%,p < 0.001)和多药(100%比62.8%,p = 0.001)发生率显著高于幸存者。相反,低能量坠落在幸存者中更为常见(74.7%比20.0%,p < 0.001),而从楼梯或床上坠落和高能创伤在非幸存者中更为常见(均p < 0.05)。在多因素logistic回归中,AF (OR: 6.112; 95% CI: 1.612-23.176; p = 0.008)、头部创伤(OR: 16.514; 95% CI: 4.925-55.367; p < 0.001)和脑血管疾病(OR: 6.725; 95% CI: 2.219-20.385; p = 0.001)成为30天死亡率的独立预测因子。虽然在单因素分析中,正常的窦性心律与生存率相关(p = 0.034),但在多因素建模中,它并没有保持独立的显著性。房颤患者的30天生存率明显低于无房颤患者(65.0% vs 96.3%, p = 0.001)。结论:这项前瞻性研究表明,心电图异常——尤其是心房颤动——是老年创伤患者30天死亡率的有力预测因素。当与头部创伤和脑血管疾病一起评估时,其预后价值进一步增强。这些发现强调了心电图作为一种快速、实用、无创的工具,可以在老年骨折患者的急诊护理中进行早期风险分层和临床决策。
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来源期刊
Journal of Clinical Medicine
Journal of Clinical Medicine MEDICINE, GENERAL & INTERNAL-
CiteScore
5.70
自引率
7.70%
发文量
6468
审稿时长
16.32 days
期刊介绍: Journal of Clinical Medicine (ISSN 2077-0383), is an international scientific open access journal, providing a platform for advances in health care/clinical practices, the study of direct observation of patients and general medical research. This multi-disciplinary journal is aimed at a wide audience of medical researchers and healthcare professionals. Unique features of this journal: manuscripts regarding original research and ideas will be particularly welcomed.JCM also accepts reviews, communications, and short notes. There is no limit to publication length: our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible.
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