Synchronous Gallbladder Cancer and Distal Cholangiocarcinoma Without Pancreaticobiliary Maljunction: A Case Report With Literature Review.

IF 1.7 4区医学 Q4 ONCOLOGY

Anticancer research Pub Date : 2025-10-01 DOI:10.21873/anticanres.17812

Shota Uemura, Yuki Kitano, Tatsunori Miyata, Teruki Sako, Yuki Hisano, Rumi Itoyama, Shigeki Nakagawa, Hirohisa Okabe, Hiromitsu Hayashi, Masaaki Iwatsuki

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引用次数: 0

Abstract

Background/aim: Reports of synchronous cancers in the biliary tract without pancreaticobiliary maljunction (PBM) are exceedingly rare. We present a case of synchronous gallbladder cancer and distal cholangiocarcinoma occurring in the absence of PBM.

Case report: A 60-year-old man presented with abdominal pain and jaundice. Preoperative imaging findings revealed a 23 mm tumor in the gallbladder and a 38 mm tumor in the distal bile duct, without signs of PBM. Preoperative diagnosis included gallbladder cancer (cT2N0M0, stage II) and distal cholangiocarcinoma (cT1N0M0, stage IA), and the patient underwent subtotal stomach-preserving pancreatoduodenectomy and liver segment IVb/V resection. Histopathology confirmed distinct gallbladder cancer and distal cholangiocarcinoma, without continuity between the tumors. The patient has been alive for 32 months after surgery without any signs of recurrence.

Conclusion: Although synchronous cancers in the biliary tract without PBM are rare, attention should be paid to the possibility of another lesion being present in the biliary tract during the diagnostic and treatment processes.

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同步胆囊癌和远端胆管癌无胰胆管畸形：1例报告并文献复习。

背景/目的：胆道同步癌无胰胆道异常（PBM）的报道是非常罕见的。我们报告一例在没有PBM的情况下发生的同步胆囊癌和远端胆管癌。病例报告：60岁男性，腹痛和黄疸。术前影像学显示胆囊内23毫米肿瘤，远端胆管内38毫米肿瘤，无PBM征象。术前诊断为胆囊癌（cT2N0M0， II期）和远端胆管癌（cT1N0M0， IA期），行保胃胰十二指肠次全切除术和肝段IVb/V切除术。组织病理学证实明显的胆囊癌和远端胆管癌，肿瘤之间没有连续性。术后患者存活32个月，无复发迹象。结论：虽然胆道同步癌无PBM少见，但在诊断和治疗过程中应注意胆道内存在其他病变的可能性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Anticancer research 医学-肿瘤学

CiteScore

3.70

自引率

10.00%

发文量

566

审稿时长

2 months

期刊介绍： ANTICANCER RESEARCH is an independent international peer-reviewed journal devoted to the rapid publication of high quality original articles and reviews on all aspects of experimental and clinical oncology. Prompt evaluation of all submitted articles in confidence and rapid publication within 1-2 months of acceptance are guaranteed. ANTICANCER RESEARCH was established in 1981 and is published monthly (bimonthly until the end of 2008). Each annual volume contains twelve issues and index. Each issue may be divided into three parts (A: Reviews, B: Experimental studies, and C: Clinical and Epidemiological studies). Special issues, presenting the proceedings of meetings or groups of papers on topics of significant progress, will also be included in each volume. There is no limitation to the number of pages per issue.