Electrochemically Modified Sensor Based on Reduced Graphene Oxide–Molybdenum Disulfide–Doped Poly(p-Aminobenzene Sulfonic Acid) Nanocomposite Film for the Detection of Morphine

IF 2.8 4区化学 Q3 CHEMISTRY, PHYSICAL

Electrocatalysis Pub Date : 2025-05-13 DOI:10.1007/s12678-025-00957-3

Pinky Abraham, Renjini Sadhana, Pavitha Pushpakaran Anitha, Akhilash Mohanan Pillai

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Abstract

The present study explores the potential of molybdenum disulfide–reduced graphene oxide/poly(p-aminobenzene sulfonic acid) (MoS₂-rGO/poly(p-ABSA)) for the detection of morphine (MO). The developed nanocomposites have an interconnected 3D network structure, in which the organic conducting polymer poly(p-ABSA) forms a uniform coating over the surface of the MoS₂-rGO composite. The composite film synthesis has been optimized to improve the electrocatalytic behavior of the developed sensor. The synergetic effect of MoS₂-rGO and poly(p-ABSA) composites contributed towards the excellent electrocatalytic activity of the developed sensor against MO. A low detection limit of 76 nM with a good regression between MO concentration and peak currents (R² = 0.99) has been achieved within the range of 50 nM to 30 µM. The fabricated sensor was successfully employed to determine MO in real samples and the results showed that it exhibited better reliability for real samples assay. Further, the potential of MoS₂-rGO/poly(p-ABSA)-based sensor as a commendable electrochemical sensing platform for simple and sensitive detection of various analytes has also been proposed.

Graphical Abstract

查看原文本刊更多论文

基于还原氧化石墨烯-二硫化钼掺杂聚对氨基苯磺酸纳米复合膜的电化学修饰传感器用于吗啡检测

本研究探讨了二硫化钼还原氧化石墨烯/聚（对氨基苯磺酸）（MoS2-rGO/聚（p-ABSA））检测吗啡（MO）的潜力。所开发的纳米复合材料具有相互连接的三维网络结构，其中有机导电聚合物聚（p-ABSA）在MoS2-rGO复合材料表面形成均匀的涂层。为了提高传感器的电催化性能，对复合膜的合成进行了优化。MoS2-rGO和poly（p-ABSA）复合材料的协同作用使得所开发的传感器对MO具有优异的电催化活性。在50 nM至30µM范围内，MO浓度与峰值电流之间具有良好的回归关系（R2 = 0.99），检测限为76 nM。该传感器成功地应用于实际样品中MO的测定，结果表明该传感器对实际样品的测定具有较好的可靠性。此外，还提出了基于MoS2-rGO/poly（p-ABSA）的传感器作为一种值得称赞的电化学传感平台的潜力，用于简单灵敏地检测各种分析物。图形抽象

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来源期刊

Electrocatalysis CHEMISTRY, PHYSICAL-ELECTROCHEMISTRY

CiteScore

4.80

自引率

6.50%

发文量

审稿时长

>12 weeks

期刊介绍： Electrocatalysis is cross-disciplinary in nature, and attracts the interest of chemists, physicists, biochemists, surface and materials scientists, and engineers. Electrocatalysis provides the unique international forum solely dedicated to the exchange of novel ideas in electrocatalysis for academic, government, and industrial researchers. Quick publication of new results, concepts, and inventions made involving Electrocatalysis stimulates scientific discoveries and breakthroughs, promotes the scientific and engineering concepts that are critical to the development of novel electrochemical technologies. Electrocatalysis publishes original submissions in the form of letters, research papers, review articles, book reviews, and educational papers. Letters are preliminary reports that communicate new and important findings. Regular research papers are complete reports of new results, and their analysis and discussion. Review articles critically and constructively examine development in areas of electrocatalysis that are of broad interest and importance. Educational papers discuss important concepts whose understanding is vital to advances in theoretical and experimental aspects of electrochemical reactions.