Electrochemical Synthesis of Isoxazolines from Aldoximes and EWG-Substituted Alkenes Enabling by In Situ Generated Hypervalent Iodine Compounds

Abstract

We developed the electrochemical synthesis of isoxazolines from aldoximes and EWG-substituted alkenes with the assistance of the in situ generated hypervalent iodine compounds. A wide range of substituted isoxazolines possessing fungicidal activity were obtained in 20–48% yields under constant current conditions in an undivided cell.