Bleb morphology following mitomycin-C sponge versus subconjunctival injection in deep sclerectomy for pediatric congenital glaucoma: A case report

IF 0.7 Q4 SURGERY

International Journal of Surgery Case Reports Pub Date : 2025-09-22 DOI:10.1016/j.ijscr.2025.111976

Dania A. Bamefleh , Mohammed A. Halawani , Saad Alosaimi , Raghad Alonazi

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Abstract

Introduction and importance

Congenital glaucoma poses a complex surgical challenge. Mitomycin-C (MMC) is frequently used to enhance surgical success, though the optimal method of application remains debated.

Case presentation

We present a pediatric case of bilateral congenital glaucoma where two different MMC application methods were used: subconjunctival injection in one eye and sponge application in the other.

Clinical discussion

Despite initial IOP reduction in both eyes, the eye treated with sponge application showed progressive bleb thinning and compromise. The subconjunctival injection resulted in a stable, diffuse bleb with better long-term outcomes.

Conclusion

This case provides comparative intra-patient evidence favoring subconjunctival injection for improved bleb morphology and stability in pediatric glaucoma.

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丝裂霉素- c海绵与结膜下注射在儿童先天性青光眼深巩膜切除术中的泡形态对比：1例报告

外阴青光眼是一项复杂的手术挑战。丝裂霉素c （MMC）经常用于提高手术成功率，尽管最佳应用方法仍存在争议。我们报告一例小儿双侧先天性青光眼，采用两种不同的MMC应用方法：一只眼结膜下注射和另一只眼海绵应用。尽管最初双眼的IOP降低，但海绵敷眼后的眼睛显示出进行性的水泡变薄和妥协。结膜下注射产生稳定的弥漫性水泡，长期效果较好。结论本病例为支持结膜下注射改善小儿青光眼水泡形态和稳定性提供了比较的患者内部证据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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