Quantifying the flash effect and its dependence on average dose rate in vivo for 6 MeV electron and 6 MV photon beams

Abstract

This study shows that an increase in average dose rate delays the onset, and reduces the severity, of radiation induced skin toxicity in mice following hemi-thorax irradiation. The FLASH sparing effect’s magnitude and dependence on dose rate appear similar following irradiations using 6 MV photon and 6 MeV electron beams.