Personalized Thyroidology: Molecular Rewiring of Thyroid Nodule Management.

IF 10.2 1区医学 Q1 ONCOLOGY

Clinical Cancer Research Pub Date : 2025-09-26 DOI:10.1158/1078-0432.ccr-25-2474

Kartik Sehgal

引用次数: 0

Abstract

Multi-gene molecular testing panels demonstrated excellent performance characteristics for evaluation of indeterminate thyroid nodules and independently risk-stratified advanced tumor stage in the Chinese population. Findings support incorporating cost-conscious molecular diagnostics in an integrated pathway along with clinical, sonographic and cytologic features, while underscoring need for prospective validation in future studies.

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个体化甲状腺学：甲状腺结节管理的分子重组。

在中国人群中，多基因分子检测小组在评估不确定甲状腺结节和独立风险分层的晚期肿瘤分期方面表现出优异的性能特征。研究结果支持将具有成本意识的分子诊断与临床、超声和细胞学特征结合起来，同时强调需要在未来的研究中进行前瞻性验证。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Cancer Research 医学-肿瘤学

CiteScore

20.10

自引率

1.70%

发文量

1207

审稿时长

2.1 months

期刊介绍： Clinical Cancer Research is a journal focusing on groundbreaking research in cancer, specifically in the areas where the laboratory and the clinic intersect. Our primary interest lies in clinical trials that investigate novel treatments, accompanied by research on pharmacology, molecular alterations, and biomarkers that can predict response or resistance to these treatments. Furthermore, we prioritize laboratory and animal studies that explore new drugs and targeted agents with the potential to advance to clinical trials. We also encourage research on targetable mechanisms of cancer development, progression, and metastasis.