{"title":"Elevated plasma p-tau217 in newborns: developmental signal or synaptic stress marker?","authors":"Caterina Motta, Chiara Giuseppina Bonomi, Alessandro Martorana","doi":"10.1093/braincomms/fcaf335","DOIUrl":null,"url":null,"abstract":"<p><p>The finding of elevated plasma p-tau217 in newborns raises the question of whether it represents a developmental signal or an early marker of synaptic stress, offering new insights into the biology of tau in the human brain.</p>","PeriodicalId":93915,"journal":{"name":"Brain communications","volume":"7 5","pages":"fcaf335"},"PeriodicalIF":4.5000,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12455416/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Brain communications","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/braincomms/fcaf335","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
The finding of elevated plasma p-tau217 in newborns raises the question of whether it represents a developmental signal or an early marker of synaptic stress, offering new insights into the biology of tau in the human brain.