{"title":"A Flavin-dependent Monooxygenase Favors the Formation of (6S)-α-Bitter Acids in Hop Glandular Trichomes.","authors":"Chengyong Feng, Baoxiu Liu, Peipei Zhao, Liying Ma, Jianxu Li, Guodong Wang","doi":"10.1016/j.xplc.2025.101528","DOIUrl":null,"url":null,"abstract":"<p><p>Beer flavors in hop glandular trichomes: In hops (Humulus lupulus L., Cannabaceae), the glandular trichomes on the female cones are highly efficient metabolic factories that produce the specialized metabolites shaping beer quality. Feng et al. identify the long-sought (6S)-α-bitter-acid synthase, a flavin-dependent monooxygenase that catalyzes the final enzymatic step in the biosynthesis of (6S)-α-bitter acids in hop glandular trichomes.</p>","PeriodicalId":52373,"journal":{"name":"Plant Communications","volume":" ","pages":"101528"},"PeriodicalIF":11.6000,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Plant Communications","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1016/j.xplc.2025.101528","RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Beer flavors in hop glandular trichomes: In hops (Humulus lupulus L., Cannabaceae), the glandular trichomes on the female cones are highly efficient metabolic factories that produce the specialized metabolites shaping beer quality. Feng et al. identify the long-sought (6S)-α-bitter-acid synthase, a flavin-dependent monooxygenase that catalyzes the final enzymatic step in the biosynthesis of (6S)-α-bitter acids in hop glandular trichomes.
期刊介绍:
Plant Communications is an open access publishing platform that supports the global plant science community. It publishes original research, review articles, technical advances, and research resources in various areas of plant sciences. The scope of topics includes evolution, ecology, physiology, biochemistry, development, reproduction, metabolism, molecular and cellular biology, genetics, genomics, environmental interactions, biotechnology, breeding of higher and lower plants, and their interactions with other organisms. The goal of Plant Communications is to provide a high-quality platform for the dissemination of plant science research.