Factors Influencing Indoor Xylene Concentrations and Biomarkers in the General Population Based on the 2020-2021 KNHANES.

IF 2.8 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Mi-Ji Kim, SangJin Park, Ahra Kim, Joo Hyun Sung
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引用次数: 0

Abstract

Purpose: Xylene, a widely used aromatic hydrocarbon, is associated with various health concerns due to its industrial and environmental exposure. While recent studies have raised concerns about its health effects on the general population, research on factors influencing xylene exposure in non-industrial settings remains limited. In this study, we aimed to analyze factors affecting indoor xylene concentrations and biomarkers in the general population using data from the 8th Korea National Health and Nutrition Examination Survey (KNHANES).

Materials and methods: We analyzed the data of 1098 participants who completed indoor air quality and biomarker testing within 1 month and had no liver or kidney disease. Environmental and individual factors were analyzed, and logistic regression was performed to identify determinants of indoor xylene concentrations and xylene biomarkers.

Results: Environmental factors such as building age within 5 years, recent house repairs within 6 months, and the use of air cleaners or air fresheners were significantly associated with higher indoor xylene concentrations. Among individual factors, high-risk occupations for xylene exposure, such as agricultural or fishery workers, machine operators, functional or assembly workers, and simple laborers, were associated with increased biomarker levels. Additionally, smoking status and body mass index were associated with xylene biomarkers.

Conclusion: This study identified key environmental and individual factors influencing xylene exposure in the general population. These findings highlight the importance of mitigating exposure risks through targeted interventions and the need for further research to reduce the potential health effects of xylene exposure.

基于2020-2021年KNHANES的普通人群室内二甲苯浓度和生物标志物的影响因素
目的:二甲苯是一种广泛使用的芳香烃,由于其工业和环境暴露而与各种健康问题有关。虽然最近的研究引起了人们对其对一般人群健康影响的关注,但对非工业环境中影响二甲苯接触的因素的研究仍然有限。在这项研究中,我们旨在分析影响室内二甲苯浓度和生物标志物的因素,使用来自第八次韩国国家健康和营养检查调查(KNHANES)的数据。材料和方法:我们分析了1098名参与者的数据,这些参与者在1个月内完成了室内空气质量和生物标志物检测,没有肝脏或肾脏疾病。分析了环境和个体因素,并进行了logistic回归,以确定室内二甲苯浓度和二甲苯生物标志物的决定因素。结果:房屋楼龄在5年内、房屋最近装修在6个月内、使用空气净化器或空气清新剂等环境因素与室内二甲苯浓度升高有显著关系。在个体因素中,暴露于二甲苯的高风险职业,如农业或渔业工人、机器操作员、功能或装配工人以及简单劳动者,与生物标志物水平升高有关。此外,吸烟状况和体重指数与二甲苯生物标志物相关。结论:本研究确定了影响普通人群二甲苯暴露的关键环境和个人因素。这些发现强调了通过有针对性的干预措施减轻接触风险的重要性,以及需要进一步研究以减少二甲苯接触对健康的潜在影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Yonsei Medical Journal
Yonsei Medical Journal 医学-医学:内科
CiteScore
4.50
自引率
0.00%
发文量
167
审稿时长
3 months
期刊介绍: The goal of the Yonsei Medical Journal (YMJ) is to publish high quality manuscripts dedicated to clinical or basic research. Any authors affiliated with an accredited biomedical institution may submit manuscripts of original articles, review articles, case reports, brief communications, and letters to the Editor.
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