Composite Porous Materials Made of Polyvinylpyrrolidone and Sodium Alginate and Double (Manganese and Strontium)-Substituted Tricalcium Phosphate for Medicine

IF 0.3 Q4 MATERIALS SCIENCE, MULTIDISCIPLINARY

Inorganic Materials: Applied Research Pub Date : 2025-09-24 DOI:10.1134/S2075113325701497

I. V. Fadeeva, A. B. Mikhailova, G. A. Davidova, L. I. Akhmetov, O. S. Antonova, K. K. Churakova, I. I. Selezneva

引用次数: 0

Abstract

Porous composite materials have been developed with a matrix composed of a mixture of polyvinylpyrrolidone (PVP) and sodium alginate (ALG), in which ceramic particles of double (manganese- and strontium)-substituted tricalcium phosphate (TCP) are distributed. X-ray diffraction analysis (XRD) demonstrated that the main crystalline phase of the (manganese and strontium)-substituted TCP is whitlockite. In vitro studies revealed that all tested materials are not adhesive to cells and exhibit no cytotoxic or inhibitory effects on them. The porous composite materials characterized by a high rate of bioreabsorption of ceramic particles and a strong potential for antibacterial activity and osteoinductive properties due to ion diffusion and changes in the surface layer properties can be used in reconstructive surgery for the restoration of bone tissue function.

Abstract Image

查看原文本刊更多论文

聚乙烯吡咯烷酮与海藻酸钠及双（锰锶）取代磷酸三钙制备的医用复合多孔材料

以聚乙烯吡咯烷酮（PVP）和海藻酸钠（ALG）为基体，制备了双（锰-锶）取代磷酸三钙（TCP）陶瓷颗粒的多孔复合材料。x射线衍射分析（XRD）表明，（锰锶）取代TCP的主要晶相为惠特洛克石。体外研究表明，所有被试材料都不粘附细胞，对细胞没有细胞毒性或抑制作用。多孔复合材料具有较高的陶瓷颗粒生物吸收率，并且由于离子扩散和表面层性质的改变而具有很强的抗菌活性和骨诱导性能的潜力，可用于重建手术以恢复骨组织功能。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Inorganic Materials: Applied Research Engineering-Engineering (all)

CiteScore

0.90

自引率

0.00%

发文量

199

期刊介绍： Inorganic Materials: Applied Research contains translations of research articles devoted to applied aspects of inorganic materials. Best articles are selected from four Russian periodicals: Materialovedenie, Perspektivnye Materialy, Fizika i Khimiya Obrabotki Materialov, and Voprosy Materialovedeniya and translated into English. The journal reports recent achievements in materials science: physical and chemical bases of materials science; effects of synergism in composite materials; computer simulations; creation of new materials (including carbon-based materials and ceramics, semiconductors, superconductors, composite materials, polymers, materials for nuclear engineering, materials for aircraft and space engineering, materials for quantum electronics, materials for electronics and optoelectronics, materials for nuclear and thermonuclear power engineering, radiation-hardened materials, materials for use in medicine, etc.); analytical techniques; structure–property relationships; nanostructures and nanotechnologies; advanced technologies; use of hydrogen in structural materials; and economic and environmental issues. The journal also considers engineering issues of materials processing with plasma, high-gradient crystallization, laser technology, and ultrasonic technology. Currently the journal does not accept direct submissions, but submissions to one of the source journals is possible.