Ravi Sankar Tulluru DM, Karthik Gopinath DM, Viji Samuel Thomson DM, John Jose E DM, Ommen K. George DM
{"title":"Coronary Artery Perforation During PCI","authors":"Ravi Sankar Tulluru DM, Karthik Gopinath DM, Viji Samuel Thomson DM, John Jose E DM, Ommen K. George DM","doi":"10.1016/j.jaccas.2025.105068","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Coronary artery perforation (CAP) is an uncommon but serious complication of percutaneous coronary intervention, with a mortality rate of 10% to 20%. Its relevance is increasing with procedural complexity and expanded device use.</div></div><div><h3>Case Summary</h3><div>We present a 10-year, single-center case series of 21 CAP cases, highlighting 5 key cases: type III CAP treated with a covered stent complicated by side branch occlusion; calcified perforation complicated by stent thrombosis; distal wire perforation with fatal outcome; chronic total occlusion-related CAP managed with coiling and surgery; and type IV CAP with delayed deterioration. Overall, type III CAP was most common (52%), and the left anterior descending artery was most frequently involved (57%). Management included covered stent in 71%, coiling in 14%, and surgery in 2 cases. Four patients died, and 2 patients developed stent thrombosis or in-stent restenosis.</div></div><div><h3>Discussion</h3><div>This series emphasizes CAP mechanisms; treatment strategies; and the importance of timely recognition, imaging guidance, and institutional preparedness.</div></div>","PeriodicalId":14792,"journal":{"name":"JACC. Case reports","volume":"30 29","pages":"Article 105068"},"PeriodicalIF":0.0000,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"JACC. Case reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666084925018480","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
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Abstract
Background
Coronary artery perforation (CAP) is an uncommon but serious complication of percutaneous coronary intervention, with a mortality rate of 10% to 20%. Its relevance is increasing with procedural complexity and expanded device use.
Case Summary
We present a 10-year, single-center case series of 21 CAP cases, highlighting 5 key cases: type III CAP treated with a covered stent complicated by side branch occlusion; calcified perforation complicated by stent thrombosis; distal wire perforation with fatal outcome; chronic total occlusion-related CAP managed with coiling and surgery; and type IV CAP with delayed deterioration. Overall, type III CAP was most common (52%), and the left anterior descending artery was most frequently involved (57%). Management included covered stent in 71%, coiling in 14%, and surgery in 2 cases. Four patients died, and 2 patients developed stent thrombosis or in-stent restenosis.
Discussion
This series emphasizes CAP mechanisms; treatment strategies; and the importance of timely recognition, imaging guidance, and institutional preparedness.