{"title":"Iatrogenic Reopening of a Congenital VSD After TAVR","authors":"Thomas J. Mason MD, Lauren T. Lastinger MD","doi":"10.1016/j.jaccas.2025.105228","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Transcatheter aortic valve replacement (TAVR) has become an increasingly used technique for patients with severe aortic stenosis who are at high risk of perioperative mortality during surgical valve replacement.</div></div><div><h3>Case Summary</h3><div>Here we describe the first case to our knowledge of a patient with a congenital perimembranous ventricular septal defect with prior spontaneous closure who experienced a post-TAVR acquired intracardiac shunt (AICS) due to the reopening of her ventricular septal defect, which caused new-onset heart failure and required surgical closure.</div></div><div><h3>Discussion</h3><div>AICS is a known complication of TAVR, but its risk in patients with congenital heart disease, particularly of the intraventricular septum, is poorly understood.</div></div><div><h3>Take-Home Messages</h3><div>In patients with congenital heart disease, detailed structural imaging should be obtained to better understand the anatomy before TAVR. Additionally, any patient with new-onset heart failure post-TAVR should be promptly evaluated for AICS.</div></div>","PeriodicalId":14792,"journal":{"name":"JACC. Case reports","volume":"30 29","pages":"Article 105228"},"PeriodicalIF":0.0000,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"JACC. Case reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S266608492502008X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
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Abstract
Background
Transcatheter aortic valve replacement (TAVR) has become an increasingly used technique for patients with severe aortic stenosis who are at high risk of perioperative mortality during surgical valve replacement.
Case Summary
Here we describe the first case to our knowledge of a patient with a congenital perimembranous ventricular septal defect with prior spontaneous closure who experienced a post-TAVR acquired intracardiac shunt (AICS) due to the reopening of her ventricular septal defect, which caused new-onset heart failure and required surgical closure.
Discussion
AICS is a known complication of TAVR, but its risk in patients with congenital heart disease, particularly of the intraventricular septum, is poorly understood.
Take-Home Messages
In patients with congenital heart disease, detailed structural imaging should be obtained to better understand the anatomy before TAVR. Additionally, any patient with new-onset heart failure post-TAVR should be promptly evaluated for AICS.