Strain-Relief-Driven Rearrangement of [2.2]Paracyclophane Derivatives in the Synthesis of Biarylophanes.

IF 5 1区化学 Q1 CHEMISTRY, ORGANIC

Organic Letters Pub Date : 2025-09-23 DOI:10.1021/acs.orglett.5c03249

Aynaz Ziadkhani,Sourav Biswas,Jian-Bin Lin,Yuming Zhao,Huck K Grover,Graham J Bodwell

引用次数: 0

Abstract

The prospect of applying the Scholl reaction to [2.2]paracyclophanes without oxidative bridge cleavage was investigated using a set of three aryl-substituted derivatives. In each case, rupture of the [2.2]paracyclophane framework could not be circumvented but led instead to a set of structurally unusual fluorescent biarylophanes (ΦF up to 0.60) with differing regioselectivity in the final ring closure.

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[2.2]副环环烷衍生物在双环烷合成中的重排。

使用一组三个芳基取代衍生物，研究了将Scholl反应应用于[2.2]副环烷而不发生氧化桥裂解的前景。在每种情况下，[2.2]副环双亲双亲双亲双亲双亲双亲双亲双亲双亲双亲双亲双亲双亲双亲双亲双亲双亲双亲双亲双亲双亲双亲双亲双亲双亲双亲双亲双亲双亲。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Organic Letters 化学-有机化学

CiteScore

9.30

自引率

11.50%

发文量

1607

审稿时长

1.5 months

期刊介绍： Organic Letters invites original reports of fundamental research in all branches of the theory and practice of organic, physical organic, organometallic,medicinal, and bioorganic chemistry. Organic Letters provides rapid disclosure of the key elements of significant studies that are of interest to a large portion of the organic community. In selecting manuscripts for publication, the Editors place emphasis on the originality, quality and wide interest of the work. Authors should provide enough background information to place the new disclosure in context and to justify the rapid publication format. Back-to-back Letters will be considered. Full details should be reserved for an Article, which should appear in due course.