EQALM recommendations for the analytical performance specifications for blood smear interpretation in haematology: a need for standardization.

IF 3.7 2区医学 Q1 MEDICAL LABORATORY TECHNOLOGY

Clinical chemistry and laboratory medicine Pub Date : 2025-09-24 DOI:10.1515/cclm-2025-1011

Stéphanie Albarède, Erika Sárkàny, Barbara De la Salle

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引用次数: 0

Abstract

Objectives: The European Organization for External Quality Assurance Providers in Laboratory Medicine (EQALM) Haematology Working Group (WG) has previously provided two guidelines to support the standardization of haematology blood smear external quality assessment (EQA) (Vives CJL, Albarède S, Flandrin G, Heller S, Horvath K, Houwen B, et al. Guidelines for blood smear preparation and staining procedure for setting up an external quality assessment scheme for blood smear interpretation. Part I: control material. Clin Chem Lab Med 2004;42:922-6; Vives CJL, Van Blerk M, Albarède S, Gutierrez G, Heller S, Nordin G, et al. Guidelines for setting up an external quality assessment scheme for blood smear interpretation. Part II: survey preparation, statistical evaluation and reporting. Clin Chem Lab Med 2006;44:1039-43) but these recommendations did not include analytical performance specifications. In this paper the WG provides advice on the performance specifications for the evaluation of blood cell identification, comments on morphological characteristics and diagnostic hypothesis.

Methods: To develop these specifications, the WG made a survey of the practices in use by EQALM members and provided a standard set of EQA data, provided by one of the members, for performance evaluation.

Results: The results of this exercise show a variation in the performance assessment outcomes from one EQA provider to another, suggesting that a degree of standardisation would be of benefit to participating laboratories.

Conclusions: The WG has provided advice on common performance specifications, based on model 1 of the Milan Consensus (Sandberg S, Fraser CG, Horvath AR, Jansen R, Jones G, Oosterhuis W, et al. Defining analytical performance specifications: consensus statement from the 1st strategic conference of the European federation of clinical chemistry and laboratory medicine. Clin Chem Lab Med 2015;53:833-5).

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EQALM对血液学中血液涂片解释分析性能规范的建议：需要标准化。

目的：欧洲检验医学外部质量保证提供者组织（EQALM）血液学工作组（WG）先前提供了两个指南来支持血液学血液涂片外部质量评估（EQA）的标准化（Vives CJL, albar S, Flandrin G, Heller S, Horvath K， Houwen B等）。制定血液涂片制备及染色程序指引，以建立血液涂片解释的外部质素评估计划。第一部分：控制材料。中华临床医学杂志2004；42:922-6；张建军，张建军，张建军，等。建立血液涂片判读外部质素评估计划的指引。第二部分：调查准备、统计评估和报告。临床化学实验室医学2006；44:10 . 39-43)，但这些建议不包括分析性能规范。在本文中，工作组就血细胞鉴定评估的性能规范、形态学特征和诊断假设提出了建议。方法：为了制定这些规范，工作组对EQALM成员使用的实践进行了调查，并提供了一组标准的EQA数据，由其中一个成员提供，用于绩效评估。结果：本练习的结果显示了绩效评估结果从一个EQA供应商到另一个的变化，这表明一定程度的标准化将有利于参与实验室。结论：工作组根据米兰共识模型1 （Sandberg S, Fraser CG, Horvath AR, Jansen R, Jones G， Oosterhuis W等人）提供了关于通用性能规范的建议。定义分析性能规范：来自欧洲临床化学和检验医学联合会第一届战略会议的共识声明。临床化学检验医学2015；53:83 - 35)。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical chemistry and laboratory medicine 医学-医学实验技术

CiteScore

11.30

自引率

16.20%

发文量

306

审稿时长

3 months

期刊介绍： Clinical Chemistry and Laboratory Medicine (CCLM) publishes articles on novel teaching and training methods applicable to laboratory medicine. CCLM welcomes contributions on the progress in fundamental and applied research and cutting-edge clinical laboratory medicine. It is one of the leading journals in the field, with an impact factor over 3. CCLM is issued monthly, and it is published in print and electronically. CCLM is the official journal of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) and publishes regularly EFLM recommendations and news. CCLM is the official journal of the National Societies from Austria (ÖGLMKC); Belgium (RBSLM); Germany (DGKL); Hungary (MLDT); Ireland (ACBI); Italy (SIBioC); Portugal (SPML); and Slovenia (SZKK); and it is affiliated to AACB (Australia) and SFBC (France). Topics: - clinical biochemistry - clinical genomics and molecular biology - clinical haematology and coagulation - clinical immunology and autoimmunity - clinical microbiology - drug monitoring and analysis - evaluation of diagnostic biomarkers - disease-oriented topics (cardiovascular disease, cancer diagnostics, diabetes) - new reagents, instrumentation and technologies - new methodologies - reference materials and methods - reference values and decision limits - quality and safety in laboratory medicine - translational laboratory medicine - clinical metrology Follow @cclm_degruyter on Twitter!