Intradural calcifying pseudoneoplasm of the neuraxis in the lumbosacral canal: Two case reports and review of the literature

IF 0.7 Q4 SURGERY

International Journal of Surgery Case Reports Pub Date : 2025-09-21 DOI:10.1016/j.ijscr.2025.111966

Shuo Han , Guang-Ming Wang , Da-Wei Dai , Dan-Feng Zhang

{"title":"Intradural calcifying pseudoneoplasm of the neuraxis in the lumbosacral canal: Two case reports and review of the literature","authors":"Shuo Han , Guang-Ming Wang , Da-Wei Dai , Dan-Feng Zhang","doi":"10.1016/j.ijscr.2025.111966","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Calcifying pseudoneoplasms of the neuraxis (CAPNON) are benign and slowly growing fibro-osseous lesions of the nervous system.</div></div><div><h3>Methods</h3><div>We report two rare cases of spinal CAPNON and provide a literature review.</div></div><div><h3>Results</h3><div>A 33-year-old woman with back pain underwent lumbar magnetic resonance imaging (MRI), revealing a large intradural mass (1.5 × 0.9 × 10.6cm<sup>3</sup>) at L2-S1. Postoperative MRI scan performed 3 years after surgery confirmed no recurrence. A 64-year-old woman with lower limb numbness and gait instability underwent lumbar MRI, revealing an L3 intradural mass (1.1 × 0.3 × 1.6cm<sup>3</sup>). Lower limb numbness were resolved after surgery during 1 year follow-up.</div></div><div><h3>Conclusion</h3><div>Accurate recognition of CAPNON is essential to guide appropriate surgical intervention due to its favorable prognosis. In these situations, complete resection and radiological follow-up are highly recommended.</div></div>","PeriodicalId":48113,"journal":{"name":"International Journal of Surgery Case Reports","volume":"136 ","pages":"Article 111966"},"PeriodicalIF":0.7000,"publicationDate":"2025-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Surgery Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2210261225011526","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"SURGERY","Score":null,"Total":0}

引用次数: 0

Abstract

Background

Calcifying pseudoneoplasms of the neuraxis (CAPNON) are benign and slowly growing fibro-osseous lesions of the nervous system.

Methods

We report two rare cases of spinal CAPNON and provide a literature review.

Results

A 33-year-old woman with back pain underwent lumbar magnetic resonance imaging (MRI), revealing a large intradural mass (1.5 × 0.9 × 10.6cm³) at L2-S1. Postoperative MRI scan performed 3 years after surgery confirmed no recurrence. A 64-year-old woman with lower limb numbness and gait instability underwent lumbar MRI, revealing an L3 intradural mass (1.1 × 0.3 × 1.6cm³). Lower limb numbness were resolved after surgery during 1 year follow-up.

Conclusion

Accurate recognition of CAPNON is essential to guide appropriate surgical intervention due to its favorable prognosis. In these situations, complete resection and radiological follow-up are highly recommended.

查看原文本刊更多论文

腰骶管神经轴硬膜内钙化假瘤：2例报告及文献复习

背景：神经轴钙化假性肿瘤（CAPNON）是一种良性的、生长缓慢的神经系统纤维骨性病变。方法报告2例罕见的脊柱CAPNON病例，并进行文献复习。结果33岁女性腰痛患者行腰椎磁共振成像（MRI），发现L2-S1处硬膜内肿物大（1.5 × 0.9 × 10.6cm3）。术后3年MRI扫描证实无复发。64岁女性，下肢麻木、步态不稳，行腰椎MRI检查，发现L3硬膜内肿块（1.1 × 0.3 × 1.6cm3）。术后1年随访，下肢麻木消失。结论CAPNON预后良好，对其进行准确识别对指导手术治疗具有重要意义。在这种情况下，强烈建议完全切除并进行放射随访。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊