Comparative assessment of classical and fractional Casson models for hemodynamic flow in inclined vessels

IF 6.3 2区 医学 Q1 BIOLOGY
Wan Faezah Wan Azmi, Ahmad Qushairi Mohamad, Lim Yeou Jiann, Sharidan Shafie
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引用次数: 0

Abstract

Mathematical modelling in hemodynamic applications is essential for rapidly developing hypotheses and predicting experimental results within vascular systems. For such models to be reliable, they must closely replicate real-world physiological conditions. This study aims to analytically compare classical and fractional Casson fluid models for blood flow in inclined cylinders, incorporating slip velocity effects, magnetohydrodynamics (MHD), and porous media. Recent studies suggest that fractional fluid models offer advantages by capturing memory effects and non-local behaviour in blood flow. The Caputo-Fabrizio fractional derivative is employed to resolve singularities inherent in classical approaches, facilitating improved modelling of viscoelastic blood behaviour under pulsatile conditions. Analytical solutions for both models are attained using Laplace and finite Hankel transforms. Graphical results illustrate velocity and temperature profiles, highlighting key parameters such as magnetic influence, Casson fluid properties, Darcy's law, fractional derivatives, slip velocity, Grashof number, and inclination angle. Findings show that increased slip velocity augments fluid flow near the cylinder wall, with greater blood flow observed when the artery is oriented vertically upward. Results reveal that the fractional model can mitigate unphysical velocity spikes (common in classical models). The analytical results provide a benchmark for validating numerical models and demonstrate the fractional model's ability to address mathematical limitations of classical approaches. Although the study is theoretical, it provides a foundation for future mapping of physiological parameters and experimental validation.
倾斜血管血流动力学经典和分数卡森模型的比较评价
数学建模在血流动力学应用是必不可少的快速发展假设和预测血管系统内的实验结果。为了使这些模型可靠,它们必须密切地复制现实世界的生理条件。本研究的目的是分析比较经典的卡森流体模型和分数卡森流体模型在倾斜圆柱体中的血流,包括滑移速度效应、磁流体力学(MHD)和多孔介质。最近的研究表明,分数流体模型通过捕捉血流中的记忆效应和非局部行为提供了优势。Caputo-Fabrizio分数阶导数用于解决经典方法中固有的奇点,促进了脉动条件下粘弹性血液行为的改进建模。利用拉普拉斯变换和有限汉克尔变换得到了这两个模型的解析解。图形结果说明了速度和温度分布,突出显示了关键参数,如磁影响、卡森流体性质、达西定律、分数导数、滑移速度、格拉什夫数和倾角。结果表明,滑移速度的增加增加了圆柱壁上的流体流动,当动脉垂直向上定向时,观察到更大的血流量。结果表明,分数阶模型可以减轻非物理速度峰值(在经典模型中常见)。分析结果为验证数值模型提供了基准,并展示了分数模型解决经典方法的数学局限性的能力。虽然该研究是理论性的,但它为未来生理参数的绘制和实验验证提供了基础。
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来源期刊
Computers in biology and medicine
Computers in biology and medicine 工程技术-工程:生物医学
CiteScore
11.70
自引率
10.40%
发文量
1086
审稿时长
74 days
期刊介绍: Computers in Biology and Medicine is an international forum for sharing groundbreaking advancements in the use of computers in bioscience and medicine. This journal serves as a medium for communicating essential research, instruction, ideas, and information regarding the rapidly evolving field of computer applications in these domains. By encouraging the exchange of knowledge, we aim to facilitate progress and innovation in the utilization of computers in biology and medicine.
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