{"title":"Type 2 diabetes mellitus: Isn't it time to update the terminology?","authors":"Arkiath Veettil Raveendran","doi":"10.4239/wjd.v16.i9.107517","DOIUrl":null,"url":null,"abstract":"<p><p>There is a paradigm shift in the approach to the treatment of type 2 diabetes mellitus (T2DM) based on recent research. \"Twin cycle hypothesis\" and remission of diabetes proved that diabetes is a disease due to excess fat accumulation above the personal fat threshold. Hence, weight reduction and, whenever possible, achievement of remission has become therapeutic target for the management of T2DM. Increasing evidence suggests that T2DM is a part of the spectrum of diseases caused by excess fat accumulation. Hence, it indeed is the need of the hour to update the terminologies to indicate that T2DM is part of the disease spectrum of excess fat accumulation to improve awareness among healthcare professionals and the public to achieve overall holistic management of the disease spectrum. In this short article, we analyze these factors and propose a new terminology for adaptation worldwide.</p>","PeriodicalId":48607,"journal":{"name":"World Journal of Diabetes","volume":"16 9","pages":"107517"},"PeriodicalIF":4.6000,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12444309/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"World Journal of Diabetes","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.4239/wjd.v16.i9.107517","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
引用次数: 0
Abstract
There is a paradigm shift in the approach to the treatment of type 2 diabetes mellitus (T2DM) based on recent research. "Twin cycle hypothesis" and remission of diabetes proved that diabetes is a disease due to excess fat accumulation above the personal fat threshold. Hence, weight reduction and, whenever possible, achievement of remission has become therapeutic target for the management of T2DM. Increasing evidence suggests that T2DM is a part of the spectrum of diseases caused by excess fat accumulation. Hence, it indeed is the need of the hour to update the terminologies to indicate that T2DM is part of the disease spectrum of excess fat accumulation to improve awareness among healthcare professionals and the public to achieve overall holistic management of the disease spectrum. In this short article, we analyze these factors and propose a new terminology for adaptation worldwide.
期刊介绍：
The WJD is a high-quality, peer reviewed, open-access journal. The primary task of WJD is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of diabetes. In order to promote productive academic communication, the peer review process for the WJD is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJD are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in diabetes. Scope: Diabetes Complications, Experimental Diabetes Mellitus, Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus, Diabetes, Gestational, Diabetic Angiopathies, Diabetic Cardiomyopathies, Diabetic Coma, Diabetic Ketoacidosis, Diabetic Nephropathies, Diabetic Neuropathies, Donohue Syndrome, Fetal Macrosomia, and Prediabetic State.
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