Thymolipoma as a Rare Cause of Myasthenia Gravis.

IF 0.8 Q4 CLINICAL NEUROLOGY
Neuro-Ophthalmology Pub Date : 2025-01-06 eCollection Date: 2025-01-01 DOI:10.1080/01658107.2025.2449873
Natalie Si-Yi Lee, Levi Bassin, Kate Ahmad
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引用次数: 0

Abstract

We present two cases of a rare thymic tumor presenting with ocular myasthenia gravis. Patient A was a male in his 40s who presented with bilateral diplopia. Investigations revealed negative myasthenic antibodies and positive jitter on single fiber electromyography. Patient B was a female in her 20s who presented with bilateral and fluctuating ptosis and diplopia, and was found to have positive acetylcholine receptor antibodies. Both patients demonstrated thymic hyperplasia on computed tomography chest and underwent robotic thymectomy. Pathology of the excised thymic tissue confirmed thymolipoma. We discuss the incidence, presentation, and management of thymolipomatous myasthenia gravis and present robotic thymectomy as a minimally invasive surgical treatment for thymolipoma.

胸腺脂肪瘤是重症肌无力的罕见病因。
我们报告两例罕见的胸腺肿瘤,表现为眼部重症肌无力。患者A是一名40多岁的男性,患有双侧复视。调查显示肌无力抗体阴性,单纤维肌电图阳性。患者B是一名20多岁的女性,表现为双侧和波动性上睑下垂和复视,发现乙酰胆碱受体抗体阳性。这两名患者在胸部计算机断层扫描上都表现出胸腺增生,并接受了机器人胸腺切除术。切除的胸腺组织病理证实为胸腺脂肪瘤。我们讨论了胸腺脂肪瘤性重症肌无力的发病率、表现和治疗,并介绍了机器人胸腺切除术作为胸腺脂肪瘤的微创手术治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Neuro-Ophthalmology
Neuro-Ophthalmology 医学-临床神经学
CiteScore
1.80
自引率
0.00%
发文量
51
审稿时长
>12 weeks
期刊介绍: Neuro-Ophthalmology publishes original papers on diagnostic methods in neuro-ophthalmology such as perimetry, neuro-imaging and electro-physiology; on the visual system such as the retina, ocular motor system and the  pupil; on neuro-ophthalmic aspects of the orbit; and on related fields such as migraine and ocular manifestations of neurological diseases.
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