Association between the degree of Parkinson's disease progression and the oral environment.

IF 2.6 4区医学 Q2 CLINICAL NEUROLOGY

Neurologia i neurochirurgia polska Pub Date : 2025-09-22 DOI:10.5603/pjnns.106300

Airi Yamamoto, George Umemoto, Shinsuke Mizutani, Shinsuke Fujioka, Yoshio Tsuboi, Haruhiko Kashiwazaki

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引用次数: 0

Abstract

Introduction: Aim of this study was to examine the relationship between the degree of Parkinson's disease (PD) progression and the oral environment in patients with PD.

Material and methods: Fifty patients with PD [mean age, 64.9 ± 8.5 years old; mean Hoehn and Yahr (HY) stage, 3.2 ± 0.8] were recruited. The patients were divided into a mild/moderate group (HY stage 2-3) and a severe group (HY stage 4-5), and the oral environment was assessed using the Oral Health Assessment Tool (OHAT) score.

Results: The OHAT scores for all participants were positively correlated with the age (rho = 0.27, p < 0.05), disease duration (rho = 0.28, p < 0.05), and MMSE score (rho = -0.28, p < 0.05). Multiple linear regression analyses showed that, among the OHAT items, "tongue," "saliva," and "lips" were associated with the age, disease duration, and MMSE, respectively (β = 0.021, p = 0.008; β = 0.027, p = 0.010; β = -1.974, p = 0.041, respectively).

Conclusions: The results of this study suggest the possibility of an association between the degree of PD progression, such as age and disease duration, and the deterioration of the oral environment. These results encourage specialized personnel to pay attention to the tongue and dry mouth condition, especially for older PD patients with a long disease duration.

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帕金森病进展程度与口腔环境的关系。

前言：本研究旨在探讨帕金森病（PD）进展程度与患者口腔环境的关系。材料与方法：50例PD患者[平均年龄64.9±8.5岁；平均Hoehn和Yahr （HY）期（3.2±0.8）。将患者分为轻度/中度组（HY期2-3）和重度组（HY期4-5），采用口腔健康评估工具（OHAT）评分对口腔环境进行评估。结果：所有参与者的OHAT评分与年龄（rho = 0.27, p < 0.05）、病程（rho = 0.28, p < 0.05）、MMSE评分（rho = -0.28, p < 0.05）呈正相关。多元线性回归分析显示，在OHAT项目中，“舌头”、“唾液”和“嘴唇”分别与年龄、病程和MMSE相关（β = 0.021, p = 0.008; β = 0.027, p = 0.010; β = -1.974, p = 0.041）。结论：本研究结果提示PD进展程度（如年龄和病程）与口腔环境恶化之间可能存在关联。这些结果鼓励专业人员关注舌头和口干的情况，特别是对于病程较长的老年PD患者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neurologia i neurochirurgia polska 医学-临床神经学

CiteScore

4.20

自引率

27.60%

发文量

128

审稿时长

6-12 weeks

期刊介绍： Polish Journal of Neurology and Neurosurgery is an official journal of the Polish Society of Neurology and the Polish Society of Neurosurgeons, aimed at publishing high quality articles within the field of clinical neurology and neurosurgery, as well as related subspecialties. For more than a century, the journal has been providing its authors and readers with the opportunity to report, discuss, and share the issues important for every-day practice and research advances in the fields related to neurology and neurosurgery.