Increasing Prevalence of Pediatric Type 2 Diabetes in the Republic of Ireland: A National Cross-Sectional Study.

IF 5.6 3区 医学 Q2 ENDOCRINOLOGY & METABOLISM
Pediatric Diabetes Pub Date : 2025-09-11 eCollection Date: 2025-01-01 DOI:10.1155/pedi/8892271
Katie Lynam, Michael J O'Grady
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Abstract

Aims: To establish the current prevalence of type 2 diabetes in children and adolescents aged under 16 years in the Republic of Ireland, to identify modes of presentation, patient characteristics, comorbidities, management, and outcomes. Methods: We conducted a cross-sectional study of children and adolescents aged under 16 years with a diagnosis of type 2 diabetes in September 2023 using a standardized proforma. This was circulated to all clinicians providing care to children with diabetes in all 19 centers in the Republic of Ireland. Results: Thirty-two cases of type 2 diabetes were identified, giving an estimated prevalence in children and adolescents under 16 years of 3/100,000 population, a significant increase from 1.2/100,000 population in 2015 (p  < 0.004). This was due to increased prevalence rates in, both White and Asian populations, as well as an increase in the size of the Asian population under 16. Nineteen (59%) were girls. Median duration of diabetes was 1.2 (0.1-4.9) years. Median body mass index (BMI) z-score at diagnosis was identical to the 2015 study (+2.3). Sixteen (50%) achieved the target HbA1c specified by the International Society for Pediatric and Adolescent Diabetes (ISPAD) of 48 mmol/mol (6.5%) or less. Completion of screening for comorbidities and complications of type 2 diabetes were not in accordance with guidelines. Conclusion: There has been a significant increase in the prevalence of type 2 diabetes in under 16's in a short timeframe. Establishment of a National Diabetes Register will facilitate ongoing monitoring of disease epidemiology in this and other age cohorts.

爱尔兰共和国儿童2型糖尿病患病率增加:一项全国性横断面研究。
目的:确定爱尔兰共和国16岁以下儿童和青少年2型糖尿病的当前患病率,以确定表现模式、患者特征、合并症、管理和结局。方法:我们对2023年9月诊断为2型糖尿病的16岁以下儿童和青少年进行了一项横断面研究,使用标准化形式。这份报告在爱尔兰共和国所有19个中心分发给所有为糖尿病儿童提供护理的临床医生。结果:发现32例2型糖尿病,估计16岁以下儿童和青少年的患病率为3/10万人,较2015年的1.2/10万人显著增加(p < 0.004)。这是由于白人和亚洲人口的患病率增加,以及16岁以下亚洲人口的规模增加。其中19名(59%)是女孩。糖尿病的中位病程为1.2(0.1-4.9)年。诊断时的中位体重指数(BMI) z分数与2015年的研究相同(+2.3)。16例(50%)达到了国际儿科和青少年糖尿病学会(ISPAD)规定的48 mmol/mol(6.5%)或更低的HbA1c目标。2型糖尿病合并症和并发症的筛查未按照指南完成。结论:在短时间内,16岁以下2型糖尿病的患病率显著增加。建立国家糖尿病登记册将有助于对这一年龄组和其他年龄组的疾病流行病学进行持续监测。
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来源期刊
Pediatric Diabetes
Pediatric Diabetes 医学-内分泌学与代谢
CiteScore
6.60
自引率
14.70%
发文量
141
审稿时长
4-8 weeks
期刊介绍: Pediatric Diabetes is a bi-monthly journal devoted to disseminating new knowledge relating to the epidemiology, etiology, pathogenesis, management, complications and prevention of diabetes in childhood and adolescence. The aim of the journal is to become the leading vehicle for international dissemination of research and practice relating to diabetes in youth. Papers are considered for publication based on the rigor of scientific approach, novelty, and importance for understanding mechanisms involved in the epidemiology and etiology of this disease, especially its molecular, biochemical and physiological aspects. Work relating to the clinical presentation, course, management and outcome of diabetes, including its physical and emotional sequelae, is considered. In vitro studies using animal or human tissues, whole animal and clinical studies in humans are also considered. The journal reviews full-length papers, preliminary communications with important new information, clinical reports, and reviews of major topics. Invited editorials, commentaries, and perspectives are a regular feature. The editors, based in the USA, Europe, and Australasia, maintain regular communications to assure rapid turnaround time of submitted manuscripts.
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