Ilenia D'Alessio, Nicola Monzio-Compagnoni, Greta Salinetti, Joseph DuBose, Benjamin W Starnes, Elina Quiroga, Davide Benasconi, Mario D'Oria, Sandro Lepidi, Pierantonio Rimoldi, Valerio Stefano Tolva
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引用次数: 0
Abstract
Objectives: Blunt thoracic aortic injuries (BTAIs) are the second leading cause of death in polytrauma patients. The majority of BTAIs occurs in males in the fifth decade, thoracic endovascular aortic repair (TEVAR) is the gold standard for the treatment. The role of gender in the natural history of BTAIs and in perioperative outcomes is still not clear.
Methods: A retrospective multicenter cohort study was conducted using dataset of the Aortic Trauma Foundation (ATF) Global Registry. The primary outcome of this study was to determine if gender correlates with a different severity of the aortic injury. The secondary outcome was to determine if gender affects perioperative complications after TEVAR.
Results: Within a total of 942 patients enrolled from February 2016 to May 2022, 623 patients met the inclusion criteria. Seventy-seven percent were males (age 44.2±17.9 years). The BTAIs grades according to the Society for Vascular Surgery (SVS) classification was: 158 (25.4%) grade I, 89 (14.3%) grade II, 310 (49.8%) grade III and 66 (10.6%) grade IV. Males showed a higher probability to develop more severe aortic lesions compared to women (OR 1.500 CI95%; p=0.035). TEVAR was performed in 384 patients and results reveal a higher risk of intra and perioperative complications in women, despite no statistical significance was demonstrated (p >0.05).
Conclusions: Gender related differences in the natural history of BTAIs and in the outcomes of patients undergoing TEVAR are present. Females show a lower risk of developing more severe aortic injuries, but they seem to develop more intra and perioperative complications when treated with TEVAR.
期刊介绍:
Annals of Vascular Surgery, published eight times a year, invites original manuscripts reporting clinical and experimental work in vascular surgery for peer review. Articles may be submitted for the following sections of the journal:
Clinical Research (reports of clinical series, new drug or medical device trials)
Basic Science Research (new investigations, experimental work)
Case Reports (reports on a limited series of patients)
General Reviews (scholarly review of the existing literature on a relevant topic)
Developments in Endovascular and Endoscopic Surgery
Selected Techniques (technical maneuvers)
Historical Notes (interesting vignettes from the early days of vascular surgery)
Editorials/Correspondence