A case of colon cancer with secondary pancreatic head metastasis treated via radioactive iodine-125 seed implantation

Abstract

Introduction

Metastatic pancreatic tumors are rare, accounting for only 2 % of pancreatic malignancies, with colon cancer representing just 1.3 % of these cases. Currently, there is no consensus on the therapeutic approach for secondary pancreatic metastasis from colon cancer. Presentation of case: This report details the treatment of an 81-year-old female patient with secondary pancreatic head metastasis from colon cancer. In December 2023, the patient underwent ultrasound-guided percutaneous puncture radioactive Iodine-125 seed implantation radiotherapy. The procedure was successful, with no significant complications. Follow-up at seven months post-procedure showed complete regression of the pancreatic lesion, and the patient remained in good health at nine months.

Discussion

Colon cancer commonly metastasizes to lymph nodes, liver, lungs, and bones, with pancreatic metastasis being rare. Treatment for pancreatic metastases is complex, but Iodine-125 seed implantation has shown good efficacy for colorectal cancer-related pancreatic metastases. This minimally invasive method offers effective tumor control and recovery.

Conclusion

These findings suggest that Iodine-125 seed implantation is a promising, minimally invasive approach for managing pancreatic metastasis secondary to colorectal cancer, providing effective local control and favorable recovery outcomes.