Evaluation of Potentially Inappropriate Prescriptions Among the Geriatric Population in Tabuk, Saudi Arabia via the STOPP/START Criteria, Version 3: A Multicentric Study

IF 2.1 4区医学 Q3 HEALTH CARE SCIENCES & SERVICES

Journal of evaluation in clinical practice Pub Date : 2025-09-21 DOI:10.1111/jep.70279

Kousalya Prabahar

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引用次数: 0

Abstract

Background

Older populations are prone to various chronic diseases and takes polypharmacy, which can lead to potentially inappropriate medications (PIMs), causing several complications. This research aimed to estimate PIMs and potential prescribing omissions (PPOs) in older adults via the STOPP/START criteria, version 3.

Methods

This multicentric retrospective observational study was executed among subjects aged ≥ 65 years, who were hospitalized at two Ministry hospitals from July 2023 to June 2024. The medicines of the geriatric population were assessed for PIMs/PPOs via the STOPP/START criteria, version 3. The data were scrutinized via SPPSS 27. Descriptive statistics were performed for qualitative and quantitative data. Multinomial logistic regression was applied to evaluate the effects of sex, age, comorbidities and medicines on PIMs and PPOs. Multiple linear regression analysis was conducted to evaluate potential multicollinearity among the predictors associated with PIMs and PPOs.

Results

In total, 385 subjects were included in this study. The participants' mean age was 75.7 ± 8.76 years and 50.13% were male. Among the study population, 48.83% had potentially inappropriate prescriptions, 37.66% with PIMs and 20.52% with PPOs. In total, 190 PIMs and 108 PPOs were identified, and the most frequently prescribed PIM was calcium channel blockers (20%). Comorbidities were significantly associated with PIMs and PPOs.

Conclusion

Overall, 48.83% of the prescriptions were potentially inappropriate. The percentage of PIMs/PPOs is lower in our population than in previous versions of the STOPP/START criteria. However, scheduled audits should be performed to keep the PIMs/PPOs at the lowest range. A comprehensive list of medications that are appropriate or inappropriate for use in older adults should be established, and prescribers should consult this list before prescribing to help prevent potentially inappropriate prescriptions.

查看原文本刊更多论文

通过STOPP/START标准评估沙特阿拉伯Tabuk老年人群中可能不适当的处方，版本3：一项多中心研究

年龄较大的人群容易患各种慢性疾病并服用多种药物，这可能导致潜在的不适当药物（PIMs），导致多种并发症。本研究旨在通过STOPP/START标准，版本3来估计老年人的pim和潜在处方遗漏（PPOs）。方法对2023年7月至2024年6月在两所部属医院住院的年龄≥65岁的患者进行多中心回顾性观察性研究。通过STOPP/START标准第3版对老年人群的药物进行PIMs/PPOs评估。通过SPPSS 27对数据进行了仔细检查。对定性和定量数据进行描述性统计。采用多项logistic回归评价性别、年龄、合并症和药物对PIMs和PPOs的影响。采用多元线性回归分析评估与PIMs和PPOs相关的预测因子之间可能存在多重共线性关系。结果本研究共纳入385名受试者。参与者平均年龄为75.7±8.76岁，男性占50.13%。在研究人群中，有潜在不当处方的占48.83%，pim占37.66%，PPOs占20.52%。总共鉴定出190例PIM和108例PPOs，最常用的PIM是钙通道阻滞剂（20%）。合并症与PIMs和PPOs显著相关。结论总体而言，48.83%的处方存在潜在不适宜处方。在我们的人口中，pim / ppo的百分比比以前版本的STOPP/START标准要低。但是，应该执行计划审计，以将pim / ppo保持在最低范围内。应建立适合或不适合老年人使用的综合药物清单，开处方者应在开处方前查阅该清单，以帮助预防可能不适当的处方。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of evaluation in clinical practice 医学-卫生保健

CiteScore

4.80

自引率

4.20%

发文量

143

审稿时长

3-8 weeks

期刊介绍： The Journal of Evaluation in Clinical Practice aims to promote the evaluation and development of clinical practice across medicine, nursing and the allied health professions. All aspects of health services research and public health policy analysis and debate are of interest to the Journal whether studied from a population-based or individual patient-centred perspective. Of particular interest to the Journal are submissions on all aspects of clinical effectiveness and efficiency including evidence-based medicine, clinical practice guidelines, clinical decision making, clinical services organisation, implementation and delivery, health economic evaluation, health process and outcome measurement and new or improved methods (conceptual and statistical) for systematic inquiry into clinical practice. Papers may take a classical quantitative or qualitative approach to investigation (or may utilise both techniques) or may take the form of learned essays, structured/systematic reviews and critiques.