Updated Results of a Phase 1 First-in-Human Study of Cemsidomide (CFT7455), a Novel MonoDAC® Degrader, with Dexamethasone in Patients with Relapsed/Refractory Multiple Myeloma (RRMM)

IF 2.7 4区医学 Q2 HEMATOLOGY

Clinical Lymphoma, Myeloma & Leukemia Pub Date : 2025-09-01 DOI:10.1016/S2152-2650(25)03456-1

Binod Dhakal, Andrew Yee, Paul Richardson, Sikander Ailawadhi, Saurabh Chhabra, Eli Muchtar, Jesus Berdeja, Shambavi Richard, Jeffrey V. Matous, Urvi Shah, Mark Schroeder, Nisha Joseph, Sumedha Javalikar, Amro Ali, Leah Leahy, Uma Chandrasekaran, Riadh Lobbardi, Rong Chu, Eunju Hurh, Leonard Reyno, Sagar Lonial

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新型MonoDAC®降解剂Cemsidomide （CFT7455）与地塞米松联合治疗复发/难治性多发性骨髓瘤（RRMM）患者的i期临床研究的最新结果

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Lymphoma, Myeloma & Leukemia ONCOLOGY-HEMATOLOGY

CiteScore

2.70

自引率

3.70%

发文量

1606

审稿时长

26 days

期刊介绍： Clinical Lymphoma, Myeloma & Leukemia is a peer-reviewed monthly journal that publishes original articles describing various aspects of clinical and translational research of lymphoma, myeloma and leukemia. Clinical Lymphoma, Myeloma & Leukemia is devoted to articles on detection, diagnosis, prevention, and treatment of lymphoma, myeloma, leukemia and related disorders including macroglobulinemia, amyloidosis, and plasma-cell dyscrasias. The main emphasis is on recent scientific developments in all areas related to lymphoma, myeloma and leukemia. Specific areas of interest include clinical research and mechanistic approaches; drug sensitivity and resistance; gene and antisense therapy; pathology, markers, and prognostic indicators; chemoprevention strategies; multimodality therapy; and integration of various approaches.