First-in-Human Study of GPRC5D-Targeted CAR T-cell Therapy CT071 with an Accelerated Manufacturing Process for the Treatment of Relapsed/Refractory Multiple Myeloma

IF 2.7 4区医学 Q2 HEMATOLOGY

Clinical Lymphoma, Myeloma & Leukemia Pub Date : 2025-09-01 DOI:10.1016/S2152-2650(25)03488-3

Lina Jin, Sinan Gu, Qianqi Ruan, Jing Lu, Wanting Qiang, Haiyan He, Xiaoqiang Fan, Jin Liu, Pei Guo, Xingxing Meng, Nishanthan Rajakumaraswamy, Deng Chen, Zonghai Li, Juan DU

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gprc5d靶向CAR - t细胞疗法CT071的首次人体研究与加速生产过程治疗复发/难治性多发性骨髓瘤

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来源期刊

Clinical Lymphoma, Myeloma & Leukemia ONCOLOGY-HEMATOLOGY

CiteScore

2.70

自引率

3.70%

发文量

1606

审稿时长

26 days

期刊介绍： Clinical Lymphoma, Myeloma & Leukemia is a peer-reviewed monthly journal that publishes original articles describing various aspects of clinical and translational research of lymphoma, myeloma and leukemia. Clinical Lymphoma, Myeloma & Leukemia is devoted to articles on detection, diagnosis, prevention, and treatment of lymphoma, myeloma, leukemia and related disorders including macroglobulinemia, amyloidosis, and plasma-cell dyscrasias. The main emphasis is on recent scientific developments in all areas related to lymphoma, myeloma and leukemia. Specific areas of interest include clinical research and mechanistic approaches; drug sensitivity and resistance; gene and antisense therapy; pathology, markers, and prognostic indicators; chemoprevention strategies; multimodality therapy; and integration of various approaches.