Theoretical and retrograde calculation of blood alcohol: wide estimates using the Academy Standards Board for calculations over an extended period of time.

IF 1
Alan H B Wu, Neal Benowitz
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Abstract

Introduction: Toxicologists defend alcohol testing from their laboratories for medicolegal cases.

Methods: A 22-year-old woman drank 144.1 g of alcohol over 8.25 hours at work. Precise details of her drinking (time, volume, and alcohol content) were provided. At her shift's end, her supervisor allowed her to drive home, during which time she caused the death of another driver. Her blood alcohol concentration (BAC) was 2.20 g/L, tested a few hours later. She did not drink alcohol after her work discharge. The decedent's family sued her employer for failure to recognize intoxication. An expert was engaged to perform both theoretical and retrograde BAC estimates based on consumption and the reported BAC, respectively.

Results: Blood alcohol concentration calculations require use of the volume of distribution and the alcohol metabolism rate. The Academy Standards Board recommends reporting a range of BAC calculations. The theoretical and retrograde calculations in this case largely matched each other, suggesting that the driver did not drink after work. Due to the long interval between alcohol intake and her work dismissal, the theoretical calculation produced a wide BAC range (1.4-4.6 g/L). The retrograde calculation range was tighter (2.6-3.1 g/L).

Discussion: A prolonged duration between drinking and testing produces a range of BAC results that can cause ambiguities in legal proceedings.

血液酒精含量的理论计算和逆行计算:使用美国科学院标准委员会在较长时期内进行计算的广泛估计。
简介:毒理学家捍卫酒精测试从他们的实验室医学法律案件。方法:一名22岁的女性在8.25小时的工作时间内饮用了144.1 g酒精。提供了她饮酒的精确细节(时间、量和酒精含量)。在她轮班结束时,她的主管允许她开车回家,在此期间,她造成了另一名司机的死亡。几小时后,她的血液酒精浓度(BAC)为2.20 g/L。她下班后没有喝酒。死者的家人起诉她的雇主未能识别醉酒。一位专家分别根据消耗量和报告的BAC进行理论和逆行BAC估计。结果:血液酒精浓度计算需要利用体积分布和酒精代谢率。学院标准委员会建议报告一系列BAC计算。在这种情况下,理论计算和逆行计算基本吻合,表明司机下班后没有喝酒。由于饮酒与下班间隔时间较长,理论计算得出的BAC范围较宽(1.4-4.6 g/L)。逆行计算范围较窄(2.6 ~ 3.1 g/L)。讨论:饮酒和检测之间的时间间隔较长,会产生一系列BAC结果,这可能会导致法律诉讼中的模糊性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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