Unexplained subcutaneous swelling: Keep echinococcosis in mind! Report of two primary extrahepatic subcutaneous echinococcosis cases and literature review.
Louis Bohard, Eléonore Brumpt, Noémie Tissot, Marie Lacoste, Olivia Chapuis, Sophie Felix, Jenny Knapp, Carole Hartmann-Gouvenot, Yannick Jeffredo, Frederic Grenouillet, Damien Montange, Anne-Pauline Bellanger, Catherine Chirouze, Solange Bresson-Hadni
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引用次数: 0
Abstract
Alveolar and cystic echinococcoses (AE and CE) are parasitic zoonoses, mainly affecting the liver. Primary extrahepatic localizations remain rare and are difficult to diagnose. We report two cases of primary subcutaneous echinococcosis and the largest literature review on the subject. The first case is an alveolar echinococcosis located in the forehead region and the second a cystic echinococcosis in the abdominal wall. To our knowledge, a primary AE location in the face has never been described before. Pre-surgical diagnosis was not made in these two cases. However, it is essential to apply specific measures, depending on the type of echinococcosis (AE or CE), to prevent parasitic dissemination and recurrence. In view of the cases presented here, prolonged albendazole can be a second-line alternative to a surgical strategy. Echinococcosis should be kept in mind for differential diagnosis of soft tissue lesions in any part of the body.
期刊介绍:
PLOS Neglected Tropical Diseases publishes research devoted to the pathology, epidemiology, prevention, treatment and control of the neglected tropical diseases (NTDs), as well as relevant public policy.
The NTDs are defined as a group of poverty-promoting chronic infectious diseases, which primarily occur in rural areas and poor urban areas of low-income and middle-income countries. Their impact on child health and development, pregnancy, and worker productivity, as well as their stigmatizing features limit economic stability.
All aspects of these diseases are considered, including:
Pathogenesis
Clinical features
Pharmacology and treatment
Diagnosis
Epidemiology
Vector biology
Vaccinology and prevention
Demographic, ecological and social determinants
Public health and policy aspects (including cost-effectiveness analyses).