Management of Hypertension and Associated Comorbidities: An Expert Consensus Statement from India.

Q3 Medicine
H N Mishra, Sadanand Shetty, Arun Chopra, Girish B Navasundi, Ashwani Mehta, Dayanand Kumbla, Peeyush Jain, Dibya K Baruah, Amit Singhal, Y S Kumar, K A Sambasivam, Anurag Sharma, Sachin Patil, Gaurav Chaudhary, Y K Singh, P K Deb, M Jawahar, Swapan K Saha, Nilesh Parshottam, Y S Rao, Dilip K Ratnani, Vikrant Vijan, P C Sarma, A Purnanad, Anand Parikh, Arun Mohanty, Biswadev B Majumdar, Dipak R Das, Harshit Gupta, Keshav Kale, Krutik Kulkarni, Miraj Modal, Nikhil Motiramani, Nimit Shah, Nishad Chitnis, Pankaj Goyal, Ragavendra, Srikanth Bodepudi, Thiyagarajan, Tirthankar Roy, U P Singh, Uttam K Saha, Vinod Kumar, Vithal D Baghi, Vivudh P Singh, Aditya Rattan, Anil Gomber, Ankur Dasgupta, Biswa R Jena, D K Garg, Dipankar Deb, Farah Ingale, Ganesh Seth, Gaurav Tripathi, K Deelip Kumar, Manoj Chitale, N Kumaralingam, Nandakumaran, P R Ramulu, Piyush Dabhi, S Pradeep, Rajeev Mehra, Sekhar Chakraborty, Sunil Dube, Sunil Kohli, T K Batabyal, T V Narayan Rao, V H Kriplani, Heena Bhojwani, Bhakti Sawant, Priyank Shah, Sanjay Jain
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引用次数: 0

Abstract

Hypertension is a leading global health concern that significantly contributes to cardiovascular (CV) and renal diseases. In India, its prevalence is rising, often coexisting with comorbidities such as type 2 diabetes mellitus (T2DM), chronic kidney disease (CKD), coronary artery disease (CAD), and metabolic syndrome (MetS). Effective hypertension management in these populations is challenging due to variations in blood pressure (BP) targets, the need for combination therapy, and the complexity of treating associated conditions such as albuminuria, nephropathy, CKD, CAD, and acute coronary syndromes (ACS). Despite advancements in treatment options, inconsistencies in clinical practice highlight the need for standardized, evidence-based recommendations. This expert consensus aims to address these gaps by guiding BP targets, optimal antihypertensive strategies, and individualized treatment approaches for high-risk patients. Key considerations include the role of renin-angiotensin-aldosterone system blockers, calcium channel blockers (CCBs), beta-blockers (BBs), sodium-glucose cotransporter-2 inhibitors, and combination therapies in improving CV and renal outcomes. By establishing clear, consensus-driven recommendations, this statement seeks to enhance hypertension management, promote early intervention, and improve patient outcomes in India.

高血压及相关合并症的管理:来自印度的专家共识声明
高血压是全球主要的健康问题,对心血管(CV)和肾脏疾病有重要影响。在印度,其患病率正在上升,通常伴有合并症,如2型糖尿病(T2DM)、慢性肾病(CKD)、冠状动脉疾病(CAD)和代谢综合征(MetS)。由于血压(BP)靶点的变化,需要联合治疗,以及治疗蛋白尿、肾病、CKD、CAD和急性冠状动脉综合征(ACS)等相关疾病的复杂性,这些人群的有效高血压管理具有挑战性。尽管治疗方案取得了进步,但临床实践中的不一致性突出了标准化、循证建议的必要性。专家共识旨在通过指导血压目标、最佳降压策略和针对高危患者的个体化治疗方法来解决这些差距。主要考虑因素包括肾素-血管紧张素-醛固酮系统阻滞剂、钙通道阻滞剂(CCBs)、β受体阻滞剂(BBs)、钠-葡萄糖共转运蛋白-2抑制剂和联合治疗在改善CV和肾脏预后中的作用。通过建立明确的、以共识为导向的建议,本声明旨在加强高血压管理,促进早期干预,并改善印度患者的预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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CiteScore
0.80
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发文量
509
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