Molecular characterization of sensitization profiles of Cannabis sativa.

IF 3.6 3区 医学 Q1 PATHOLOGY
Alessandro Toscano, Vito Sabato, Christel Mertens, Jessy Elst, Michel Van Houdt, Michiel Beyens, Margo M Hagendorens, Didier G Ebo
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引用次数: 0

Abstract

Introduction: IgE-mediated Cannabis allergy (CA) is a potentially severe immediate hypersensitivity reaction caused by exposure to cannabis derivatives, which is frequently associated with a secondary form of plant food allergy.

Areas covered: Since the first description of CA in the 1970s, the research on CA and understanding of its allergenic profile has grown. To date, five Cannabis sativa allergens have been officially registered and many others have been identified as putative. This review provides a comprehensive overview of molecular insights in the field as of 2025.

Expert opinion/commentary: Many questions concerning CA remain unanswered, and the exact clinical role of certain allergens is unclear to date. Given the increasing worldwide use of cannabis, further research is needed to fill current knowledge gaps and provide accessible and effective diagnostic tools.

大麻致敏谱的分子表征。
简介:ige介导的大麻过敏(CA)是由暴露于大麻衍生物引起的潜在严重的直接超敏反应,通常与继发性植物性食物过敏有关。涵盖领域:自20世纪70年代首次描述CA以来,对CA的研究和对其致敏性的了解不断增加。迄今为止,已经正式登记了五种大麻过敏原,并确定了许多其他过敏原。本文综述了2025年分子生物学领域的研究进展。专家意见/评论:关于CA的许多问题仍未得到解答,某些过敏原的确切临床作用至今尚不清楚。鉴于全球大麻使用量不断增加,需要进一步研究以填补目前的知识空白,并提供可获得和有效的诊断工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
6.60
自引率
0.00%
发文量
71
审稿时长
1 months
期刊介绍: Expert Review of Molecular Diagnostics (ISSN 1473-7159) publishes expert reviews of the latest advancements in the field of molecular diagnostics including the detection and monitoring of the molecular causes of disease that are being translated into groundbreaking diagnostic and prognostic technologies to be used in the clinical diagnostic setting. Each issue of Expert Review of Molecular Diagnostics contains leading reviews on current and emerging topics relating to molecular diagnostics, subject to a rigorous peer review process; editorials discussing contentious issues in the field; diagnostic profiles featuring independent, expert evaluations of diagnostic tests; meeting reports of recent molecular diagnostics conferences and key paper evaluations featuring assessments of significant, recently published articles from specialists in molecular diagnostic therapy. Expert Review of Molecular Diagnostics provides the forum for reporting the critical advances being made in this ever-expanding field, as well as the major challenges ahead in their clinical implementation. The journal delivers this information in concise, at-a-glance article formats: invaluable to a time-constrained community.
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