The nasal microbiome, inhalation exposure, and brain toxicity: A commentary

IF 3.9 3区 医学 Q2 NEUROSCIENCES
Christine Frieke Kuper , Eva A.J. Rennen , Wolfgang Kaufmann
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引用次数: 0

Abstract

The microbiome is increasingly discussed in diseases of the nervous system. The nasal microbiome is largely unexplored in neurotoxicity, while inhalation exposure to xenobiotics has been associated with neurodegenerative diseases linked to neurodegenerative diseases that are a growing health problem. The concept of a link between pathological changes of the nasal microbiome (dysbiosis) and brain neurotoxicity upon inhalation exposure is still in its early stages. In this commentary we argue that research into the nasal microbiome offers a great opportunity to obtain important information about the neurotoxicity of inhaled xenobiotics.
鼻微生物群,吸入暴露和脑毒性:评论。
微生物组在神经系统疾病中被越来越多地讨论。鼻腔微生物组在神经毒性方面还未被广泛研究,而吸入暴露于异种抗生素与神经退行性疾病有关,而神经退行性疾病是一个日益严重的健康问题。鼻微生物组病理变化(生态失调)与吸入暴露后脑神经毒性之间的联系的概念仍处于早期阶段。在这篇评论中,我们认为对鼻腔微生物组的研究提供了一个很好的机会,可以获得关于吸入异种抗生素的神经毒性的重要信息。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Neurotoxicology
Neurotoxicology 医学-毒理学
CiteScore
6.80
自引率
5.90%
发文量
161
审稿时长
70 days
期刊介绍: NeuroToxicology specializes in publishing the best peer-reviewed original research papers dealing with the effects of toxic substances on the nervous system of humans and experimental animals of all ages. The Journal emphasizes papers dealing with the neurotoxic effects of environmentally significant chemical hazards, manufactured drugs and naturally occurring compounds.
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